ID A0A091RJE0_9GRUI Unreviewed; 299 AA.
AC A0A091RJE0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=PDZ and LIM domain protein 4 {ECO:0000256|ARBA:ARBA00039369};
DE Flags: Fragment;
GN ORFNames=N332_00974 {ECO:0000313|EMBL:KFQ39357.1};
OS Mesitornis unicolor (brown roatelo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis.
OX NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ39357.1, ECO:0000313|Proteomes:UP000053369};
RN [1] {ECO:0000313|EMBL:KFQ39357.1, ECO:0000313|Proteomes:UP000053369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ39357.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, lamellipodium
CC {ECO:0000256|ARBA:ARBA00004510}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Cytoplasm, perinuclear region
CC {ECO:0000256|ARBA:ARBA00004556}. Early endosome membrane
CC {ECO:0000256|ARBA:ARBA00004469}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004469}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004469}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004125}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004125}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004125}. Recycling endosome membrane
CC {ECO:0000256|ARBA:ARBA00004159}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004159}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004159}. Synapse, synaptosome
CC {ECO:0000256|ARBA:ARBA00034102}.
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DR EMBL; KK819031; KFQ39357.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091RJE0; -.
DR Proteomes; UP000053369; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09451; LIM_RIL; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR031847; PDLI1-4/Zasp-like_mid.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24214:SF6; PDZ AND LIM DOMAIN PROTEIN 4; 1.
DR PANTHER; PTHR24214; PDZ AND LIM DOMAIN PROTEIN ZASP; 1.
DR Pfam; PF15936; DUF4749; 1.
DR Pfam; PF00412; LIM; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00132; LIM; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000053369};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 1..53
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 222..281
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 75..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ39357.1"
FT NON_TER 299
FT /evidence="ECO:0000313|EMBL:KFQ39357.1"
SQ SEQUENCE 299 AA; 32824 MW; CBE77CC6D845C47F CRC64;
INPGSKAAMA DLCPGDIILA INGESTENMT HLEAQNKIKA CMDQLLLSVN RAEGKTWSPP
VLEDGKAQAY RINIEPEPQD NGPAQSRRPM PHGAGGSPVD NKQMLNVQHH HPTRLYTNSG
SESALPGQLS GLHIAPAYSL DPLKSLPRNR NGIDVESDVY KMLQDYEKPV SEPKQSGSFR
YLQGMLEAGE NGEKVDKLSN PRNVKSPVSK LGGAMPGLQM LPECTRCGNG IVGTIVKARD
KLYHPECFMC DDCGLNLKQR GYFFIEEQLY CETHAKERVK PPEGYDVVAV YPNAKVELV
//
