ID A0A091RN43_9GRUI Unreviewed; 131 AA.
AC A0A091RN43;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Follitropin subunit beta {ECO:0000256|ARBA:ARBA00040964};
DE AltName: Full=Follicle-stimulating hormone beta subunit {ECO:0000256|ARBA:ARBA00041687};
DE AltName: Full=Follitropin beta chain {ECO:0000256|ARBA:ARBA00042045};
GN ORFNames=N332_12113 {ECO:0000313|EMBL:KFQ41240.1};
OS Mesitornis unicolor (brown roatelo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis.
OX NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ41240.1, ECO:0000313|Proteomes:UP000053369};
RN [1] {ECO:0000313|EMBL:KFQ41240.1, ECO:0000313|Proteomes:UP000053369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ41240.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Heterodimer. The active follitropin is a heterodimer composed
CC of an alpha chain/CGA shared with other hormones and a unique beta
CC chain/FSHB shown here. {ECO:0000256|ARBA:ARBA00038691}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU004069}.
CC -!- SIMILARITY: Belongs to the glycoprotein hormones subunit beta family.
CC {ECO:0000256|ARBA:ARBA00006552, ECO:0000256|RuleBase:RU004069}.
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DR EMBL; KK823493; KFQ41240.1; -; Genomic_DNA.
DR RefSeq; XP_010191418.1; XM_010193116.1.
DR AlphaFoldDB; A0A091RN43; -.
DR GeneID; 104547438; -.
DR KEGG; mui:104547438; -.
DR CTD; 2488; -.
DR OrthoDB; 5353873at2759; -.
DR Proteomes; UP000053369; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR CDD; cd00069; GHB_like; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR006208; Glyco_hormone_CN.
DR InterPro; IPR001545; Gonadotropin_bsu.
DR InterPro; IPR018245; Gonadotropin_bsu_CS.
DR PANTHER; PTHR11515:SF17; FOLLITROPIN SUBUNIT BETA; 1.
DR PANTHER; PTHR11515; GLYCOPROTEIN HORMONE BETA CHAIN; 1.
DR Pfam; PF00007; Cys_knot; 1.
DR SMART; SM00068; GHB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00261; GLYCO_HORMONE_BETA_1; 1.
DR PROSITE; PS00689; GLYCO_HORMONE_BETA_2; 1.
PE 3: Inferred from homology;
KW Hormone {ECO:0000256|RuleBase:RU004069};
KW Reference proteome {ECO:0000313|Proteomes:UP000053369};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..131
FT /note="Follitropin subunit beta"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001879374"
FT DOMAIN 19..122
FT /note="Glycoprotein hormone subunit beta"
FT /evidence="ECO:0000259|Pfam:PF00007"
SQ SEQUENCE 131 AA; 14695 MW; A7392D832AA99946 CRC64;
MKTVNCYVLL FCWKAICCNS CQLTNITIAV EREECEFCIT VNATWCSGYC FTRDPVYKYP
PVSSVQQTCT FKEVVYETVK IPGCGDHPES FYSYPVATEC HCETCDTDST DCTVRGLGPS
YCSFSQNGSN Q
//
