ID A0A091RTA8_NESNO Unreviewed; 2898 AA.
AC A0A091RTA8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Protocadherin Fat 3 {ECO:0000313|EMBL:KFQ45653.1};
DE Flags: Fragment;
GN ORFNames=N333_10054 {ECO:0000313|EMBL:KFQ45653.1};
OS Nestor notabilis (Kea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Nestor.
OX NCBI_TaxID=176057 {ECO:0000313|EMBL:KFQ45653.1, ECO:0000313|Proteomes:UP000053840};
RN [1] {ECO:0000313|EMBL:KFQ45653.1, ECO:0000313|Proteomes:UP000053840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N333 {ECO:0000313|EMBL:KFQ45653.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KK932424; KFQ45653.1; -; Genomic_DNA.
DR Proteomes; UP000053840; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 21.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.60; Cadherins; 21.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR24026; FAT ATYPICAL CADHERIN-RELATED; 1.
DR PANTHER; PTHR24026:SF125; FAT-LIKE CADHERIN-RELATED TUMOR SUPPRESSOR HOMOLOG; 1.
DR Pfam; PF00028; Cadherin; 19.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF02210; Laminin_G_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 21.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00282; LamG; 1.
DR SUPFAM; SSF49313; Cadherin-like; 21.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00232; CADHERIN_1; 10.
DR PROSITE; PS50268; CADHERIN_2; 20.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2699..2719
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..121
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 122..324
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 325..438
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 454..541
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 538..639
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 640..741
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 742..842
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 843..949
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 950..1051
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1052..1155
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1156..1241
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1253..1358
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1359..1468
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1469..1573
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1574..1675
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1676..1780
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1781..1885
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1886..1990
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1991..2095
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2106..2197
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2339..2377
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2379..2562
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2565..2602
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2604..2640
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2642..2678
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 2870..2898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2870..2891
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 2592..2601
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2630..2639
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2668..2677
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ45653.1"
FT NON_TER 2898
FT /evidence="ECO:0000313|EMBL:KFQ45653.1"
SQ SEQUENCE 2898 AA; 317831 MW; 5DFFD8E58772AFCF CRC64;
VLIKVLDNND NGPEFSHPSY DVTISEDILP DTEILQIEAI DRDEKHKLSY TIHSSIDTVS
MRKFRIDPST GVLYIAERLD HEAQDKHILN VMVRDQEFPY RRNLARVIIN VEDSNDHSPY
FTSPLYEASV FESAAVGSAV LQVTALDKDK GENAELIYTI EAGNTGNTFK IEPVLGIITL
LKEPDLTTMG QFVLSVKVAD QGSPPLSATA IVRISVTMAD NSHPKFTLKE YQAEVNENAD
IGTSVISLSA ISQSTLVYEV KDGNVDGVFT INPYSGVITS QKALDYERAS FYQLIVQATN
MAGMASNATV NIQIVDENDN PPVFLFSQYS GSISEAAPVN SIVRSASNSP LVIRATDADS
NQNALLVYQI VESTAKKYFT VDSSTGAIRT IANLDHETIA HFHFHVHVRD SGNPQLTAES
PVEVTIEVTD VNDNPPVFSQ AVFETVLLLP TYVGVEVLKV KATDPDSEIP PELTYSLIEG
NMEHFAIDSS TGVLTIKNNS LSKDHYMLIV RVSDGKFYST AMVTIMVKEA MDSGLHFTQN
FYSTSISENS TNITKIAVVN AVGNRLNEPL KYSILNPGNK FKIKSTSGVI QTTGIPFDRE
EQELYELVVE ASRELDHLRV ARVVVRVYIE DINDNAPVFI GLPYYAAVQV DAEPGTMIYR
VTAIDKDKGE NGEVSYLLKE DYGHFEIDRA SGSVTLKEAF NSDLSNIEYL VVILAKDGGN
PSLSALVELP ITIVNKAMPV FDKPFYTASV NEDVEMHTPI LSINATSPEG QGIIYIIVDG
DPYNQFNIDF DTGVLSVISP LDYEINSLFK LMVRASDALT GARAEVTVDL IINDVNDNPP
IFDQTAYNAT LSEASLIGTP VLQVVAIDAD SDNNKIVQYQ IVQDTFNSTD YFHIDSSSGL
ILTARMLDHE LIQQCSLKVR ATDNGFPPLS SEVLVSISIT DMNDNPPVFN QLIYESYVSE
LAPRGHFVTC VQASDADSSD FDRLEYSILS GNDRTSFIMD SKSGVITLSN HRKQRMEPMY
SLNVSVSDGL FTSTAQVHIQ ILGANLYSPV FSQSVYVAEV RENAAPGTKV IHVKATDGDS
GVYGQISYSI INDFAKDRFL VDSNGQILTT ERLDRENPLE SDIGIFLRAL DGGGRTTFCT
VRVIVVDEND NTPQFMTVEY RASVKADVGK GYLVTQVQAV DPDDGANSRI TYSLYSEASV
SVADLLEIDP DNGWMVTKGS FNQLKNTVLS FFVKAVDGGI PLKHSQIILP SFSQPQYSFT
IAEDTLIGST IDILHVLPNQ GALYSTVNGE LTENNKDGVF IIEQDTGLIK LDKRLDHEAN
PAFHFKVAAT IQLDRVDIVL TVDVEVKVLD VNDNKPMFET ASYDAIIMEG MPIGTKLMQV
KAVDADSSAN GQVTYTLAVE SELEKITEAF TIDSNSGWIS TLKDLDHEKD PAFTFAVVAS
DLGEALSLSS TTLVSVTVTD INDNAPIFEH DVYRGSVKES DPPGEVVAVL STWDEDTSDV
NRQVSYHITG GNPKGKFALG LVQNEWKVYV KRPLDREEQD IYYLNITATD GLFVTQAAVE
VTVTDVNDNS PVCEQVAYTA LFPEDIPSNK VILKISAKDA DIGSNGEIRY SLYGPGNNKF
LLDPENGELK SLAPLDREKI PAYSLVARAT DGGGRFCQSE IHLILEDVND NPPVFSSDHY
TACVYENTAT KALLTRVQAT DPDVGVNRKV TYSLADSADG YFSVDQSSGI IILEHPLDRE
LQSSYNISVK ASDQSIVLTL SSFATVTITV LDINDNPPVF ERRDYLVTVP EDTSPGTEVL
SVFATSQDIG TNAEIAYLIR SGNEKGKFRI NSKTGVISIF DTLDYETCKD FYLVVEAKDG
GTPALSAVTT VNVNVTDVND NAPKFSQAVY NAVISEDAAI GESVIMLIAE DLDSPSNGQI
HFSIVNGDRD NEFSVDPVLG LVKVKKKLDR ERISGYSLVI QARDSGTPPL SSSVTVNVDI
SDVNDNGPVF TPANYTAVIQ ENKPVGTSIL QLVVTDKDSF HNGPPFTFTI LTGNEEEEFT
LDPHGVLRSA VIFKHMVATE YVLCVQAKDS GKPQQVSHTY VQVRVIEESI HKPTAIPLEI
FIVTMEDDFP GGVIGKIHAT DQDVYDVLTY TLKSEQKSLF KVNTHDGKII ALGGLDNGKY
VLNVSVSDGR FQVPIDVVVH VEQLLQEMLQ NTVTIRFDNV SPEDFVGLHM HGFRRTLRNA
VLSQKQDSLH IISIQPVAGS NQLDMLFAVQ MHSGGFYKPA YLIQKLTNAR RHLENVIRIS
AILEKNCSGL DCQEQHCEQS LSIDSHSLMA YSTARISFVC PRFYRNVRCM CNGGLCPGSN
DPCLEKPCPG DMQCVGYEAN RRPFICQCPP GKLGECSGHT SLSFAGNSYI KYRVSENSKK
EEFKLALRLR TLQSNGIIMY TRANPCIILK IVDGKLWFQL DCGSGPGILG ISGRAVNDGS
WHSVFLELNR NFTSLSLDDS YVERRKAPLY FQTLSTDSSI YFGAQVQVDN IRSLTDKRTT
QVLSGFQGCL DSVVLNNTDL PLQNKRSSFA EVVGLTELKL GCVLYPDACE RHPCQNGGTC
TSVPSGGYQC NCLSQFTGRN CESEITACFP NPCRNGGSCD PIGNAFICNC KNGLTGVTCE
EDINECEREE CENGGSCVNI FGSFLCNCTP GYVGQYCGLR PVVVPNIQAG HSYVGKEELI
GIAGVLFVIF VLIILFIIFR KKVFRKNYSR NNITLVQDPA TAALLNKSNG IQFKNTRNSG
DSRNIYQEVG PPQVPVRPMA YTPCFQSDSR NNLDKIVDGL GVEHQEMTTF HPESPRILTA
RRGVVVCSVA PNLPAVSPCR SDCDSIRKST WDTGMESKGV DDAEEVTCFA GSNKGSNSEV
QSLSSFQSDS GDDNGKKW
//
