ID A0A091SBR0_NESNO Unreviewed; 980 AA.
AC A0A091SBR0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Signal peptide, CUB and EGF-like domain-containing protein 2 {ECO:0000313|EMBL:KFQ55387.1};
DE Flags: Fragment;
GN ORFNames=N333_12067 {ECO:0000313|EMBL:KFQ55387.1};
OS Nestor notabilis (Kea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Nestor.
OX NCBI_TaxID=176057 {ECO:0000313|EMBL:KFQ55387.1, ECO:0000313|Proteomes:UP000053840};
RN [1] {ECO:0000313|EMBL:KFQ55387.1, ECO:0000313|Proteomes:UP000053840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N333 {ECO:0000313|EMBL:KFQ55387.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KK947238; KFQ55387.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091SBR0; -.
DR Proteomes; UP000053840; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR24046; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24046:SF3; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF07699; Ephrin_rec_like; 2.
DR Pfam; PF14670; FXa_inhibition; 5.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00181; EGF; 10.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM01411; Ephrin_rec_like; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 4.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 5.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000053840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..41
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 84..120
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 320..358
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 790..902
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DISULFID 324..334
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ55387.1"
FT NON_TER 980
FT /evidence="ECO:0000313|EMBL:KFQ55387.1"
SQ SEQUENCE 980 AA; 109309 MW; 7028869A86AAAAE9 CRC64;
DVDECALGLD DCHPDAICQN TPKLYKCTCK VGYTGEGKKC EDIDECDNDF NGGCVHECFN
IPGNYRCTCY DGFMLAHDGH NCLDTDECMY NNGGCQHVCV NTVGSYECRC KEGFFLSDNQ
HTCIHRSEEG MSCMNKDHGC AHICRETPKG GVACECRPGF ELSKNQRSCI LTCNHGNGGC
QHTCDDADNG PICGCHPKYI MHVDGKTCLE REEAAVEILE GNATAGADVD KRVKRRLLME
TCAVNNGGCD RTCKDTSTGV HCSCPVGFTL QFDGKTCKDI DECQSNNGGC DHFCKNTVGS
FDCSCRKGFK LLTDEKSCQD IDECSFERTC DHTCINHPGT FECTCNKGYA LYGFTHCGDI
NECSVNNGGC QQLCVNTLGD YECLCHSNYK LHWNKKDCVE TKGSLPDNMS PKVLLHCIKS
GGSDRCFLSC SSDVQVFSGT QDAYTLTCGR SSHLKKKQQN TNASSWLAIK ISVTFKLNEG
KCSLKKTEMF QEGLEQMIPV MESFHYVNLT CSSGKKVHGA LSRLTATREI FITADFELET
SQKEVTDTCD VRCARKKTEK RFRKTIRTLR KTVSRDQFRI RVSGTDHEVA RKSLKLSEPQ
QSCGVGQMHV GNRCDLEQTI TCISILLWSG EPESCVLCPN KTEQDEEGQL TCNSCSSPQN
PGNQKLAGAH SVSQCRYQCS PGEYSPDGFK PCLPCPLGTY QPEAGRVSCF PCGGGLTTRH
SSASLFQDCE TKVQCSPGHF YNTTTHRCIR CTVGTYQPEF GQNYCISCPG NTTTDFDGST
NITQCKNRQC GGELGDYTGY IESPNYPGDY PANTECTWNI NPPPKRRILI VVPEIFLPIE
DECGDYLVMR KSSSSNSVTT YETCQTYERP IAFTSRSKKL WIQFKSNEGN SAKGFQVPYV
TYDEDYQELI EDIVRDGRLY ASENHQEILK DKKLIKALFD VLAHPQNYFK YTAQESREMF
PRSFIRLLRS KVSRFLRPYK
//
