GenomeNet

Database: UniProt
Entry: A0A091SYX6_9AVES
LinkDB: A0A091SYX6_9AVES
Original site: A0A091SYX6_9AVES 
ID   A0A091SYX6_9AVES        Unreviewed;      1909 AA.
AC   A0A091SYX6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   28-FEB-2018, entry version 21.
DE   RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};
DE   Flags: Fragment;
GN   ORFNames=N334_07664 {ECO:0000313|EMBL:KFQ63225.1};
OS   Pelecanus crispus (Dalmatian pelican).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Pelecanidae;
OC   Pelecanus.
OX   NCBI_TaxID=36300 {ECO:0000313|EMBL:KFQ63225.1, ECO:0000313|Proteomes:UP000054150};
RN   [1] {ECO:0000313|EMBL:KFQ63225.1, ECO:0000313|Proteomes:UP000054150}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N334 {ECO:0000313|EMBL:KFQ63225.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the voltage-dependent sodium ion permeability
CC       of excitable membranes. {ECO:0000256|RuleBase:RU361132}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- SIMILARITY: Belongs to the sodium channel (TC 1.A.1.10) family.
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361132}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; KK490096; KFQ63225.1; -; Genomic_DNA.
DR   Proteomes; UP000054150; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.350; -; 4.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR001696; Na_channel_asu.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   Pfam; PF00520; Ion_trans; 4.
DR   Pfam; PF06512; Na_trans_assoc; 1.
DR   PRINTS; PR00170; NACHANNEL.
DR   SMART; SM00015; IQ; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054150};
KW   Ion channel {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000313|EMBL:KFQ63225.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361132};
KW   Membrane {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000256|SAAS:SAAS00085096};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054150};
KW   Sodium {ECO:0000256|RuleBase:RU361132};
KW   Sodium channel {ECO:0000256|RuleBase:RU361132};
KW   Sodium transport {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000256|SAAS:SAAS00084820};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000256|SAAS:SAAS00084701};
KW   Transport {ECO:0000256|RuleBase:RU361132};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    117    142       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    187    206       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    218    239       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    245    265       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    366    383       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    403    430       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    746    764       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    776    799       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    811    835       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    856    884       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    946    969       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1181   1199       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1220   1242       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1248   1268       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1297   1323       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1421   1444       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1502   1520       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1532   1550       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1557   1582       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1619   1647       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1721   1746       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   DOMAIN      127    437       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      747    973       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      983   1175       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN     1179   1452       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1501   1756       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED       14     34       {ECO:0000256|SAM:Coils}.
FT   COILED      434    465       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFQ63225.1}.
FT   NON_TER    1909   1909       {ECO:0000313|EMBL:KFQ63225.1}.
SQ   SEQUENCE   1909 AA;  216295 MW;  C44DE959D10F4948 CRC64;
     PGPENLRPFT PASLAAIEQR IAEAEALKVK KQQVELPEEE EIKPSSDLEA GKNLPLIYGD
     PPLELIGIPL EDLDPFYKDK KTFIVLNKGK SIFRFSATPA LYLLGPFHPI RRGAIKVLIH
     SYPCPLMFIM ITILTNCVFM TLSNPPAWSK NVEYTFTGIY TFESLIKILS RGFCINDFTF
     LRDPWNWLDF MVISMAYITE FVDLGNISAL RTFRVLRALK TITVIPGLKT IVGALIQSVK
     KLSDVMILTV FCLSVFALIG LQLFMGNLRH KCVRWPPLND TLMGDLGLDN NTLANTTLYG
     NFTDGIASNF TSNSTFDFEA YINDEANFYF LEGALDALLC GNSSDAGKCP EGYQCMKAGR
     NPNYGYTSYD TFSWAFLALF RLMTQDFWEN LFQLTLRAAG KTYMIFFVVV IFLGSFYLIN
     LILAVVAMAY AEQNDATMLE EQQKEEEFQQ LMEQLKKHQE EQEKMVGGKE PARADYDQCT
     EEALGEDRVV AAKLNALANH MLLAKTGKSR EGSRDPASRP RMGLSKPCPR DGDSRAGHKA
     GAVASSLSKL TSEFPKALLR DDTPLLSPRE MEKREGIKLR ARAKGLQAMG ARIHVISSDR
     VWKPCCISAM CSGNREDQRS SSGSLPSSVA EKERNSDLNS DQDKAKDCNG QVVPKVVLER
     SATVLGVRAR LYQNHLTVGN QDGPGLEKRV GSAISVVSNA VEELEEAHQK CPPWWYKFAH
     TFLVWNCCPL WLKLKAFVKL VVMDPFVDLG ITICIVLNTV FMAMEHYPMT EEFQNVLTVG
     NLVFTGIFTA EMVLKLIALD PYEYFQQGWN IFDSIIVTLS LVELGLANVQ GLSVLRSFRL
     LRVFKLAKSW PTLNMLIKII GNSVGALGNL TLVLAIIVFI FAVVGMQLFG KSYIECVCKI
     SLDCTLPRWH MNDFFHSFLI VFRILCGEWI ETMWDCMEVA GQTMCLIVFM MVMVIGNLVV
     LNLFLALLLS SFSADSLAAS DDDGEMNNLQ IAIGRITKGI DFVKSSVLML LRRLWKGKKV
     APEEEQEHSK RDNSVLNHVD TGQEPKSEYL DGVTGKEHFF MDELDHMNFI NNPNLTVQVP
     IASEESDLYE ETSTQSDTED AKNPLSSDNA SSLCSTVDYK PPPLVEEEVA EEAEDKNEPK
     ECFTEACVKR FPCLYVDITS DKGKVWWNIR RTCFRIVEHD WFETFIVFMI LLSSGALAFE
     DIYIEQRRVI RTILEYADKV FSYVFVIEML LKWVAYGFKV YFTNAWCWLD FLIVDVSIIS
     LTANWLGYSE LGAIKSLRTL RALRPLRALS RFEGMRVVVN ALLGAIPSIM NVLLVCLIFW
     LIFSIMGVNL FAGKYYRCIN TTSGELFDIS VVNNKSDCMA LLYTNEVRWV NVKVNFDNVG
     LGYLSLLQVA TFKGWMDIMY AAVDSREIEE QPVYEINLYM YIYFVIFIIF GAFFTLNLFI
     GVIIDNFNQQ KKKISKDIFM TEEQKKYYNA MKKLGSKKPQ KPIPRPSNKF QGMVFDFVTK
     QVFDITIMIL ICLNMVTMMV ETDDQSELKT SVLYKINLVF IVIFTGECVL KMFALRYYYF
     TIGWNIFDFV VVILSILGIV LSDIIEKYFV SPTLFRVIRL ARIGRVLRLI RGAKGIRTLL
     FALMMSLPAL FNIGLLLFLV MFIYSIFGMS NFAYVKKEAG IDDIFNFETF GNSIICLFQI
     TTSAGWDGLL SPILNSGPPD CDPNLENPGS SVKGDCGNPS IGIFFFCSYI IISFLIVVNM
     YIAIILENFN VATEESSEPL CEDDFEMFYE TWEKFDPDAT QFIAYSTLSD FVDTLQEPLK
     IPKPNKIKLI TMDLPMVAGD KIHCLDILFA LTKEVLGDSG EMDALKATME EKFMAANPSK
     VSYEPITTTL KRKHEEVCAT KIQRAFRRYL LRRSVKQASY MYRHSKDED
//
DBGET integrated database retrieval system