ID A0A091T3U2_PHALP Unreviewed; 965 AA.
AC A0A091T3U2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE Flags: Fragment;
GN ORFNames=N335_02120 {ECO:0000313|EMBL:KFQ69021.1};
OS Phaethon lepturus (White-tailed tropicbird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Phaethontiformes;
OC Phaethontidae; Phaethon.
OX NCBI_TaxID=97097 {ECO:0000313|EMBL:KFQ69021.1, ECO:0000313|Proteomes:UP000053638};
RN [1] {ECO:0000313|EMBL:KFQ69021.1, ECO:0000313|Proteomes:UP000053638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N335 {ECO:0000313|EMBL:KFQ69021.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
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DR EMBL; KK437011; KFQ69021.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091T3U2; -.
DR PhylomeDB; A0A091T3U2; -.
DR Proteomes; UP000053638; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18023; DEXHc_HFM1; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFQ69021.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053638}.
FT DOMAIN 21..210
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 251..436
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 843..868
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ69021.1"
FT NON_TER 965
FT /evidence="ECO:0000313|EMBL:KFQ69021.1"
SQ SEQUENCE 965 AA; 109982 MW; 4AE34F502B37AA98 CRC64;
QFRSIFKEFP YFNYAQSKAL DDLLYTDRNF VICAPTGSGK TVMFELAITR LLMEAPLPWL
NIKVVYMAPI KALCSQRFDD WKEKFGPIGL SCKELTGDTV MDDLFEIHHA HIIITTPEKW
DSMTRRWRDN SIVQLVRLFL IDEVHVIKDE SRGATLEVVV SRMKTVQSSL WRLSENHDTV
PPLRFVAVSA TIPNAEDIAE WLSDSKMPAV CMKIDEEQRP VKLRKIVLGF PCSDNQTEFR
FDLTLNYKIA SIIQTYSEQK PALVFCATRK GVQQAASVLA KDAKFLLSIE QKQRLQRSAN
SLRDSKLRDL LMYGVAYHHA GMEISDRKII EGAFAVGDLP VLFTTSTLAM GVNLPAHLVI
IKSTMHYVGG VFQEYSETDI LQMIGRAGRP QFDTTATAVI MTRWSTREKY IQMLNGADII
ESSLHRHLVE HLNAEIVLHT VTDVTVALEW IRSTFLYIRA LKNPTHYGFS SGLDKIGIEA
KLQELCLKNL NDLSSFDLIR MDEANNFKPT ETGRLMAWYY IAFDTVKQFF MIKGTETLNE
LITMISNCTE FLDVKLRTNE KKILNSLNKD KDKITIRFPM EGKIKTREMK INCLIQAQLG
CIPIQDFTLT QDTGRIFRSG LRVTRWLSDF LASSKNNFFA FLNSLILAKC FRCKLWENSL
HVSKQLEKIG VSLSNAMVNA GLTSFKKIED TNARELELIL NRHPPFGNQI KESVLHLPKY
DLDIEQLPKY SDTLAEILVT IKLTNYEQLQ TKRTATDFHY VTLVIGDADN QVIFNQKIMD
SVLLKTGNWM KKIEVKRAFK SEDISINLIS SDYVGLDIQQ AYTVFYLTLK TLGSKVITNQ
KRKPESSFGT NYGSPQSLPA AKVDTGGRSK QEITYKKYGN RECNHRCKNK DVCGHDCCKT
GVPPKSDMNG DSKFSLYLAD LRSRNSISSV LPVKRLKMQM LNQAQNVDLK QFVFTPKSLL
PALPR
//
