ID A0A091T5P7_PHALP Unreviewed; 480 AA.
AC A0A091T5P7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Fibrinogen C-terminal domain-containing protein {ECO:0000259|PROSITE:PS51406};
GN ORFNames=N335_11051 {ECO:0000313|EMBL:KFQ69165.1};
OS Phaethon lepturus (White-tailed tropicbird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Phaethontiformes;
OC Phaethontidae; Phaethon.
OX NCBI_TaxID=97097 {ECO:0000313|EMBL:KFQ69165.1, ECO:0000313|Proteomes:UP000053638};
RN [1] {ECO:0000313|EMBL:KFQ69165.1, ECO:0000313|Proteomes:UP000053638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N335 {ECO:0000313|EMBL:KFQ69165.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-
CC identical chains (alpha, beta and gamma). The 2 heterotrimers are in
CC head to head conformation with the N-termini in a small central domain.
CC {ECO:0000256|ARBA:ARBA00025974}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; KK437475; KFQ69165.1; -; Genomic_DNA.
DR RefSeq; XP_010279889.1; XM_010281587.1.
DR AlphaFoldDB; A0A091T5P7; -.
DR GeneID; 104616540; -.
DR KEGG; plet:104616540; -.
DR CTD; 2244; -.
DR OrthoDB; 3134470at2759; -.
DR PhylomeDB; A0A091T5P7; -.
DR Proteomes; UP000053638; Unassembled WGS sequence.
DR GO; GO:0005577; C:fibrinogen complex; IEA:InterPro.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0030168; P:platelet activation; IEA:InterPro.
DR GO; GO:0051258; P:protein polymerization; IEA:InterPro.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 1.20.5.50; -; 2.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR InterPro; IPR037579; Fibrinogen.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR012290; Fibrinogen_a/b/g_coil_dom.
DR InterPro; IPR020837; Fibrinogen_CS.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR47221; FIBRINOGEN ALPHA CHAIN; 1.
DR PANTHER; PTHR47221:SF4; FIBRINOGEN GAMMA CHAIN; 1.
DR Pfam; PF08702; Fib_alpha; 1.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR SMART; SM00186; FBG; 1.
DR SMART; SM01212; Fib_alpha; 1.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF58010; Fibrinogen coiled-coil and central regions; 1.
DR PROSITE; PS00514; FIBRINOGEN_C_1; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
PE 4: Predicted;
KW Blood coagulation {ECO:0000256|ARBA:ARBA00023084};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hemostasis {ECO:0000256|ARBA:ARBA00022696};
KW Reference proteome {ECO:0000313|Proteomes:UP000053638};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..480
FT /note="Fibrinogen C-terminal domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001879794"
FT DOMAIN 223..478
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT REGION 27..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 480 AA; 54509 MW; 74EE24F5220B0E67 CRC64;
MKLLLLFLLC VSSVKSQGSI NYDDEVDSPE LGVRGHRPLD KRREAAPTLR PVAPPISGIG
YQPRPPKRVK PSDKKERITY PDAGGCKHPL EELGVLCPTG CELQTTLVKQ EKNVKSIVRD
LKDKVSKLSE TSTTFYEYVT VLDDKLVKRQ KQRKDNDDIL SQYNTEVELH YSYIKDNLDN
NIPSSLRVLR AVVDSLHKKI QKLENAIATQ MDYCRSPCAV SCNIPVVSGK ECEDIIRKGG
EVSEMYLIQP DPFVRPYRVY CDMQTDNGGW TLIQNRQDGS VNFGRVWDQY KKGFGNVAKS
GGKNYCDTPG EYWLGNDKIS QLTKIGPTEV LIEMEDWNGD KVSAHYGGFT IQNEGNKYQL
SVSNYKGNAG NALMEGASQV HGENRTMTIH NGMFFSTYDR DNDGWLTADP RKQCSKEDGG
GWWYNRCHSA NPNGRYYWGG TYSWDMAKHG TDDGVVWMNW KGSWYSMKKM SMKIRPYFPQ
//
