ID A0A091TEC5_PHALP Unreviewed; 453 AA.
AC A0A091TEC5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Bone morphogenetic protein 5 {ECO:0000313|EMBL:KFQ72781.1};
GN ORFNames=N335_06054 {ECO:0000313|EMBL:KFQ72781.1};
OS Phaethon lepturus (White-tailed tropicbird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Phaethontiformes;
OC Phaethontidae; Phaethon.
OX NCBI_TaxID=97097 {ECO:0000313|EMBL:KFQ72781.1, ECO:0000313|Proteomes:UP000053638};
RN [1] {ECO:0000313|EMBL:KFQ72781.1, ECO:0000313|Proteomes:UP000053638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N335 {ECO:0000313|EMBL:KFQ72781.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; KK449667; KFQ72781.1; -; Genomic_DNA.
DR RefSeq; XP_010283134.1; XM_010284832.1.
DR AlphaFoldDB; A0A091TEC5; -.
DR GeneID; 104619062; -.
DR KEGG; plet:104619062; -.
DR CTD; 653; -.
DR OrthoDB; 2912454at2759; -.
DR PhylomeDB; A0A091TEC5; -.
DR Proteomes; UP000053638; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19395; TGF_beta_BMP5; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF139; BONE MORPHOGENETIC PROTEIN 5; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000053638};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..453
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001880338"
FT DOMAIN 333..453
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 316..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 51640 MW; 8752D515DF6E5967 CRC64;
MNLTALKAFV GLLWNCWVLV GHAQGGLGDN HVHSSFIYRR LRNHERREIQ REILSILGLP
HRPRPFSPGK QASSAPLFML DLYNAMTNEE DTEELEYSLK GSMAGESRGI RKGYPASPNG
YSRRIQLSRM TPLTTQNPPL ASLHDTNFLN DADMVMSFVN LVERDKDFSH QRRHYKEFRF
DLTQIPHGEA VTAAEFRIYK DRSNNRFENE TIQISIYQIV KEYPNRDADL FLLDTRKAQA
SDVGWFVFDI TVTSNHWVIN PQNNLGLQLC AETGDGRSIN VKSAGLIGRH GPQSKQPFMV
AFFKASEVLF RSVRAANNKR KNQNRNKSSS QQESSRMPSV GDYNTSEQKQ ACKKHELYVS
FRDLGWQDWI IAPEGYAAFY CDGECSFPLN AHMNATNHAI VQTLVHLMFP DHVPKPCCAP
TKLNAISVLY FDDSSNVILK KYRNMVVRSC GCH
//
