ID A0A091TLE8_PELCR Unreviewed; 768 AA.
AC A0A091TLE8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033};
DE EC=7.6.2.1 {ECO:0000256|RuleBase:RU362033};
DE Flags: Fragment;
GN ORFNames=N334_10607 {ECO:0000313|EMBL:KFQ59516.1};
OS Pelecanus crispus (Dalmatian pelican).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Pelecanidae; Pelecanus.
OX NCBI_TaxID=36300 {ECO:0000313|EMBL:KFQ59516.1, ECO:0000313|Proteomes:UP000054150};
RN [1] {ECO:0000313|EMBL:KFQ59516.1, ECO:0000313|Proteomes:UP000054150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N334 {ECO:0000313|EMBL:KFQ59516.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + phospholipidSide 1 = ADP + phosphate +
CC phospholipidSide 2.; EC=7.6.2.1;
CC Evidence={ECO:0000256|RuleBase:RU362033};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362033}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362033}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IV subfamily. {ECO:0000256|RuleBase:RU362033}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362033}.
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DR EMBL; KK477753; KFQ59516.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091TLE8; -.
DR Proteomes; UP000054150; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140326; F:ATPase-coupled intramembrane lipid transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015914; P:phospholipid transport; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006539; P-type_ATPase_IV.
DR InterPro; IPR032631; P-type_ATPase_N.
DR NCBIfam; TIGR01652; ATPase-Plipid; 1.
DR PANTHER; PTHR24092:SF52; PHOSPHOLIPID-TRANSPORTING ATPASE FETA; 1.
DR PANTHER; PTHR24092; PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR Pfam; PF16209; PhoLip_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362033};
KW Magnesium {ECO:0000256|RuleBase:RU362033};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362033};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362033};
KW Reference proteome {ECO:0000313|Proteomes:UP000054150};
KW Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|RuleBase:RU362033};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362033};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362033}.
FT TRANSMEM 80..102
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT TRANSMEM 280..303
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT TRANSMEM 323..349
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362033"
FT DOMAIN 21..86
FT /note="P-type ATPase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16209"
FT NON_TER 768
FT /evidence="ECO:0000313|EMBL:KFQ59516.1"
SQ SEQUENCE 768 AA; 87448 MW; 78C975C9FD50B96B CRC64;
MSLFGLKFGK KKLKEEERQL QANNRDFNVQ FEYANNSIKT SKYNFFTFLP LNLFEQFQRI
ANAYFLFLLI LQLIPQISSL AWFTTVVPLV LVLAVSGVKD AIDDFNRHKS DKHVNNRPVQ
VLINGMLKDE KWMNVQVGDI IKLENNNFVT ADLLLLSSSE PHSLTYIETA ELDGETNLKV
KQALTVTAEL GEDLQKLTEF NGEVKCEAPN NKLDKFTGTL TLRGEKYALD NEKMLLRGCT
IRNTEWCFGL VIYAGPDTKL MQNSGKTTFK RTSIDRLMNV LVLVIFAFLA LMCLILAIGN
GIWEYDKGYY FQVYLPWAEG VNSASYSGFL MFWSYVIILN TVVPISLYVS VEIIRLGNSF
YIDWDRKMYY PLNDTPAQAR TTTLNEELGQ IKYIFSDKTG TLTQNIMCFN KCSINGKSYG
DVYDMSGQRI EINENTEKVD FSYNQLADPK FSFYDHSLVE AVKLSDGPTH RFFRLLSLCH
TVMPEEKKEG NLVYQAQSPD EGALVTAARN FGFVFRARTP ETITVVEMGE TKIYKLLAIL
DFNNVRKRMS VIVRSPEGDL TLYCKGADTI LYELLHSSCD SLKEETTEHL NEFAGEGLRT
LVVAYKNLDE DYFQDWIRRH HEASTALEGR EDKLSELYEE IEKDLMLLGA TAIEDKLQDG
VPQTIETLGK ASIKIWVLTG DKQETAMNIG YSCNLLHDDM EDVFIIEGST SDDVLNELRN
ARKKMKPDSF LDSDEINIQF EKSSKKTTVL PDEQANGVYG LVITGHSL
//
