ID A0A091U3X0_PHORB Unreviewed; 456 AA.
AC A0A091U3X0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 36.
DE SubName: Full=Ras-GEF domain-containing family member 1B {ECO:0000313|EMBL:KFQ85126.1};
DE Flags: Fragment;
GN ORFNames=N337_04226 {ECO:0000313|EMBL:KFQ85126.1};
OS Phoenicopterus ruber ruber.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Phoenicopteriformes; Phoenicopteridae;
OC Phoenicopterus.
OX NCBI_TaxID=9218 {ECO:0000313|EMBL:KFQ85126.1, ECO:0000313|Proteomes:UP000053700};
RN [1] {ECO:0000313|EMBL:KFQ85126.1, ECO:0000313|Proteomes:UP000053700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N337 {ECO:0000313|EMBL:KFQ85126.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK415377; KFQ85126.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091U3X0; -.
DR Proteomes; UP000053700; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF197; RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1B; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000053700}.
FT DOMAIN 37..167
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 207..451
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ85126.1"
FT NON_TER 456
FT /evidence="ECO:0000313|EMBL:KFQ85126.1"
SQ SEQUENCE 456 AA; 53447 MW; 03B1A1946D191F06 CRC64;
QERMPQTPPF AAMFDSSGYN RNLYQSKEDD CGGLYYHDNN LLSGSLEALI QHLVPNVDYY
PDRTYIFTFL LSSRLFMHPY ELMAKVCHLC IEQQRLSEPG LDKNRLRKIA PKILQLLTEW
TETFPYDFRD ERMMRNLKEL AQRIASGDEM YRKNVQQLLQ NLIRKLATVS QYEEVLAKIN
ATSTDRLTVL KTKPQSIQRD IITVCNDPYT LAQQLTHIEL ERLSYIGPEE FVQAFVQKDP
LDNDKSCYGD RKKTRHLQAY VEWFNRLSYL VATEICMPVK KKHRARVIEY FIDVARECFN
IGNFNSLMAI ISGMNMSSVS RLKKTWAKVK TAKFDILEHQ MDPSSNFYNY RTALRGAAQR
SLTAHSSREK IVIPFFSLLI KDIYFLNEGC ANRLPNGHVN FEKFWELAKQ VSEFMTWKQV
EPNILYLLLI AALYLASYES ESPENHIEKD RWKTLR
//
