ID A0A091U616_PHORB Unreviewed; 1245 AA.
AC A0A091U616;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|EMBL:KFQ86149.1};
DE Flags: Fragment;
GN ORFNames=N337_08063 {ECO:0000313|EMBL:KFQ86149.1};
OS Phoenicopterus ruber ruber.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Phoenicopteriformes; Phoenicopteridae;
OC Phoenicopterus.
OX NCBI_TaxID=9218 {ECO:0000313|EMBL:KFQ86149.1, ECO:0000313|Proteomes:UP000053700};
RN [1] {ECO:0000313|EMBL:KFQ86149.1, ECO:0000313|Proteomes:UP000053700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N337 {ECO:0000313|EMBL:KFQ86149.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK419297; KFQ86149.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091U616; -.
DR Proteomes; UP000053700; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13183; FERM_C_FRMPD1_FRMPD3_FRMPD4; 1.
DR CDD; cd17170; FERM_F1_FRMPD4; 1.
DR CDD; cd21943; LGNbd_FRMPD4; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR049385; FAK1-like_FERM_C.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR041779; FRMPD1/3/4_FERM_C.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46221:SF4; FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46221; FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF21477; FERM_C_FAK1; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053700}.
FT DOMAIN 29..106
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 155..470
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 759..797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 980..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1045..1125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 779..793
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1085..1105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1109..1125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ86149.1"
FT NON_TER 1245
FT /evidence="ECO:0000313|EMBL:KFQ86149.1"
SQ SEQUENCE 1245 AA; 137253 MW; D7C485E8E4E2EB3E CRC64;
FFHSHMTQSA TFEDPRIESC QITPPAPRKV EMRRDPVLGF GFVAGSEKPV VVRSVTPGGP
SEGKLIPGDQ IVMINDEPVS TAPRERVIDL VRSCKESILL TVVQPYPSPK SAFISAAKKA
RLKSNPVKVR FSEEVIINGQ VSETVKDNSL LFMPNVLKVY LENGQTKSFR FDCSTSIKDV
ILTLQEKLSI KCIEHFSLML EQRVEGSGTK LLLLHEQETL TQVTQRPSSH KMRCLFRISF
VPKDPIDLLR RDPVAFEYLY VQSCNDVVQE RFGPELKYDI ALRLAALQMY IATVTTKQTQ
KISLKYIEKE WGLETFLPSA VLQSMKEKNI KKALSHLVKA NQNLVPPGKK LSALQAKVHY
LKFLSDLRLY GGRVFKATLV QGEKRSEVTL LVGPRYGISH VINTKTNLVA LLADFSHVNR
IEMFTEDETS VRVELHVLDV KPITLLMESS DAMNLACLTA GYYRLLVDSR RSIFNMANKK
ITGSQETGTE NRGKHNLLAS EWNCIPKTTT FLAEGDQETQ MSFADPKQKT VDVSESLLCQ
KEHRHLYIEN TYNSGGFDQH LGKQSDPMEA EESRNFNQPS LLSLSGLESS KKAQDSPRGA
KVSFIFGDHN LDGINPQTLG YERLLDESPE VLEKQRAIYI SNANDIKGLE LSPDAESIQF
ATNSVYATIN DGKIFGAAEG IEEPLLHDIC YAENTDDAED EDEVSCEEDI MVGEINRPAL
LSLSGSSDDI IDLTSLPPPE GDDNEDDFLL HTLNMAIAAP PPGFRDSSDE EDSQNQTTQP
RDNKEQASNL GNDDIPVSLI DAVPTNTEGK CEKGLDDAVV STLQALEALA ASEEQQTNDN
SGVAILRAYS PESSSDSGNE TNSSEMTESS ELAAAQKQSE NTARMFLTTS EGYQPLVEEQ
TEFPIAKNQA GGPGMKPSQP LAGRHAAELQ SKVVPSKQIL HSDNMEMEPE TMETKSVTDY
FSKLHMGSLV YSCTSKRKNK MTDSEVKAPA DGNATVKKQQ GTKKAETDED LKAKFGTLSA
RDSQRLSTFN VERTAFRQRW YAADDGAADK PSPETVNGKT FPRVPVLGKT ETDCKDEVDP
EVDQDDTSGL SQGENFLSDM TPVSSAKDLN DAEDTDLSAD DHPSKLPEAE QSMARLCEYH
LAKRMSSLQS EGHFSLQSSQ CSSVDAGCST GSSTCATPVE SPLCTSDVKH IISDPSMKGI
AYIPADERAA ILPNHGTTYK DLHQQPEAVC HRMTVPVVHS AINAE
//
