GenomeNet

Database: UniProt
Entry: A0A091U7E6_PHORB
LinkDB: A0A091U7E6_PHORB
Original site: A0A091U7E6_PHORB 
ID   A0A091U7E6_PHORB        Unreviewed;       403 AA.
AC   A0A091U7E6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   13-FEB-2019, entry version 12.
DE   RecName: Full=Hyaluronidase {ECO:0000256|RuleBase:RU610713};
DE            EC=3.2.1.35 {ECO:0000256|RuleBase:RU610713};
DE   AltName: Full=Hyaluronoglucosaminidase {ECO:0000256|RuleBase:RU610713};
DE   Flags: Fragment;
GN   ORFNames=N337_01659 {ECO:0000313|EMBL:KFQ85765.1};
OS   Phoenicopterus ruber ruber.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Phoenicopteriformes;
OC   Phoenicopteridae; Phoenicopterus.
OX   NCBI_TaxID=9218 {ECO:0000313|EMBL:KFQ85765.1};
RN   [1] {ECO:0000313|EMBL:KFQ85765.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N337 {ECO:0000313|EMBL:KFQ85765.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Random hydrolysis of (1->4)-linkages between N-acetyl-
CC         beta-D-glucosamine and D-glucuronate residues in hyaluronate.;
CC         EC=3.2.1.35; Evidence={ECO:0000256|RuleBase:RU610713};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 56 family.
CC       {ECO:0000256|RuleBase:RU610713}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; KK417814; KFQ85765.1; -; Genomic_DNA.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR018155; Hyaluronidase.
DR   PANTHER; PTHR11769; PTHR11769; 1.
DR   Pfam; PF01630; Glyco_hydro_56; 1.
DR   PIRSF; PIRSF038193; Hyaluronidase; 1.
DR   PRINTS; PR00846; GLHYDRLASE56.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR038193-3};
KW   Glycosidase {ECO:0000256|RuleBase:RU610713};
KW   Hydrolase {ECO:0000256|RuleBase:RU610713}.
FT   ACT_SITE    108    108       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR038193-1}.
FT   CARBOHYD    331    331       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000256|PIRSR:PIRSR038193-2}.
FT   DISULFID     19    314       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   DISULFID    184    200       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   DISULFID    339    350       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   DISULFID    344    398       {ECO:0000256|PIRSR:PIRSR038193-3}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFQ85765.1}.
FT   NON_TER     403    403       {ECO:0000313|EMBL:KFQ85765.1}.
SQ   SEQUENCE   403 AA;  46375 MW;  E509392CC9AA1393 CRC64;
     PLVSNSPFLS IWNAPTELCT ERTGVQLDMK FFSLIGSTLK TAIGQNITLF YPDRLGYYPY
     KNEVTGEAFN GGLPQLSLLE NHLKKAKEDI QFYIPSDEQF GLAVIDWENW RPVWIRNWGS
     KDIYRQESIE LVQQRDLSLS EAEARSIAKM EFEAAAKAIM LESLKLGIEM KPNRLWGYYL
     YPDCYNYDYK QNPHNYTGTC LDIEIERNNE LNWLWEESTA LYPSVYLETA LRSSRNAQLF
     VRNRVQEAIR ISYVSNSTHP LPVFVYTRPV FTDVYEEYLS QDDLVNTIGE SAALGASGIV
     IWGDMNLTQN KNTCRTLDNY LRKTLTPYLI NVTMAARICS QVLCQDSGAC ARKKWNSSDY
     LHLNPENIVI QMTKDGKYTL QGQPAFQDLQ TFIEKFDCHC YAG
//
DBGET integrated database retrieval system