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Database: UniProt
Entry: A0A091U8H5_PHALP
LinkDB: A0A091U8H5_PHALP
Original site: A0A091U8H5_PHALP 
ID   A0A091U8H5_PHALP        Unreviewed;       355 AA.
AC   A0A091U8H5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-MAY-2019, entry version 21.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 12 {ECO:0000313|EMBL:KFQ70338.1};
DE   Flags: Fragment;
GN   ORFNames=N335_11186 {ECO:0000313|EMBL:KFQ70338.1};
OS   Phaethon lepturus (White-tailed tropicbird).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Phaethontidae;
OC   Phaethon.
OX   NCBI_TaxID=97097 {ECO:0000313|EMBL:KFQ70338.1};
RN   [1] {ECO:0000313|EMBL:KFQ70338.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N335 {ECO:0000313|EMBL:KFQ70338.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822}.
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DR   EMBL; KK441515; KFQ70338.1; -; Genomic_DNA.
DR   PhylomeDB; A0A091U8H5; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003272; K_chnl_inward-rec_Kir2.2.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR013673; K_chnl_inward-rec_Kir_N.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF14; PTHR11767:SF14; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   Pfam; PF08466; IRK_N; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01325; KIR22CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:KFQ70338.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     79    103       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    153    178       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1     41       IRK_N. {ECO:0000259|Pfam:PF08466}.
FT   DOMAIN       42    183       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      190    355       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        169    169       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFQ70338.1}.
FT   NON_TER     355    355       {ECO:0000313|EMBL:KFQ70338.1}.
SQ   SEQUENCE   355 AA;  40439 MW;  6D2A37F7D5218D9B CRC64;
     RVNPYSIVSS EEDGLRLTTM PGINGFGNGK IHTRRKCRNR FVKKNGQCNV EFTNMDDKPQ
     RYIADMFTTC VDIRWRYMLL LFSLAFLVSW LLFGLIFWLI ALIHGDLENP GGDDTFKPCV
     LQVNGFVAAF LFSIETQTTI GYGFRCVTEE CPLAVFMVVV QSIVGCIIDS FMIGAIMAKM
     ARPKKRAQTL LFSHNAVVAM RDGKLCLMWR VGNLRKSHIV EAHVRAQLIK PRITEEGEYI
     PLDQIDIDVG FDKGLDRIFL VSPITILHEI NEDSPLFGIS RQDLETDDFE IVVILEGMVE
     ATAMTTQARS SYLASEILWG HRFEPVLFEE KNQYKVDYSH FHKTYEVPST PRCSA
//
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