ID A0A091UA20_PHORB Unreviewed; 2828 AA.
AC A0A091UA20;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Protocadherin Fat 2 {ECO:0000313|EMBL:KFQ87549.1};
DE Flags: Fragment;
GN ORFNames=N337_10973 {ECO:0000313|EMBL:KFQ87549.1};
OS Phoenicopterus ruber ruber.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Phoenicopteriformes; Phoenicopteridae;
OC Phoenicopterus.
OX NCBI_TaxID=9218 {ECO:0000313|EMBL:KFQ87549.1, ECO:0000313|Proteomes:UP000053700};
RN [1] {ECO:0000313|EMBL:KFQ87549.1, ECO:0000313|Proteomes:UP000053700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N337 {ECO:0000313|EMBL:KFQ87549.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KK425066; KFQ87549.1; -; Genomic_DNA.
DR Proteomes; UP000053700; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 20.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.60; Cadherins; 21.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR24025:SF23; CADHERIN-4; 1.
DR PANTHER; PTHR24025; DESMOGLEIN FAMILY MEMBER; 1.
DR Pfam; PF00028; Cadherin; 19.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF02210; Laminin_G_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 21.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00282; LamG; 1.
DR SUPFAM; SSF49313; Cadherin-like; 21.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00232; CADHERIN_1; 7.
DR PROSITE; PS50268; CADHERIN_2; 20.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053700};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2650..2670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..124
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 125..229
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 230..327
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 336..441
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 538..639
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 640..740
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 741..841
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 842..948
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 949..1050
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1051..1154
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1155..1261
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1262..1367
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1368..1475
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1476..1580
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1581..1682
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1683..1787
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1788..1892
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1893..1997
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1998..2102
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2103..2190
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2343..2514
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2517..2554
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2556..2592
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2594..2630
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 2718..2740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 2544..2553
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2582..2591
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2620..2629
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ87549.1"
FT NON_TER 2828
FT /evidence="ECO:0000313|EMBL:KFQ87549.1"
SQ SEQUENCE 2828 AA; 310406 MW; 8368554493973D8F CRC64;
RPQAFIHVID INQHRPQFLE SHYEVRIPED TPSGREILQV SATDKDKGKG LIYTIHGSVD
PKSTRLFQLD PSSGVLTTAE GFSSQPMPQH TLTVMVRDQE VPIKRNFVRV IIHVENCNLH
PPQFSSIHYE AEVLDSAVVG TEVIQVRALD QDQGANSEIH YSLQAGNGEG FFSIDPYSGI
ITVAQKLDPS RQERFTLIVK AEDQGFPQLK DSATVHVRMR PSERTPPKFP EAEYITEISE
STAVGSPLIQ VSAASLSPVS YEIKDGNGDG VFSMNYQSGL ISTQKSLDFE QVSFYQLKVR
GTNMAGAFMD AMVLIYVIDE NDNVPIFVKP SFVGWIMENA PSQSMVLDES NAPLVTHATD
ADQDSNALLV YEILEPEALK YFTVDPSTGT LTSRADIDYE LTPVFHFSVH VHDSGSPSLF
ASKPAKVTIH VKDVNDSPPV FFKDTYELSV LLPAHPGMEL LSVQAKDADS EVTYSIVEGN
LHSAFYIHPL TGLISILNAT GLGSYHELTV RAGDGLYKST ALVKLNLTQG QGTGLKFDQD
VYTATVIENS TDEKTLTVLG VKGYQLNEPL FYSLLNGKER FKMIQASGVL QTKGVKFDHE
TQDMHEVAVE VKDNRKPPRV SQATVKVYVE DVNDNPPQFE NVPYYTSVQD GTEPGDVLFQ
VSATDKDIGD NGAITYSFAE DYKYFWIDPY LGDISLKKPL DYQASNKYNL RVIAKDKGEP
PLHAEEEVVI SVRNKSNPLF QSLYYRVKVP ENIPLYTSIL HIQARSPEGL RLIYNIVEED
SLKLFSTDFK TGVLTVTGQL DYELETKHMF TVRATDTALG SFSEARVEVE VEDINDNPPI
FSQMIYTASV SESLPAQTPV VQLSASDKDS GRNKVVSYQI LDDGSDATKF FNIDASTGQI
TTAQALDYEK NQQFRMKVRA ADHGMPPLSS DALVIVDVTD INDNPPEFSQ LQYEAKVSEM
ATCGHIVIKV QALDPDSGDT TRLEYVILSG NDNRHFTINS TSGIISMFNR CKKDLESSYN
LRVSASDGVF KSTVPVYINT TNANKYSPSF RQNVYEAELA ENAEIGTKVI ELLAIDPDGG
PYGTIDYTII NKLAHEKFSI DNKGRIATLQ KLDRENSTER VIAIKVMAKD GGGKVAFCTV
KIILTDENDN PPQFKASEYT LSIQSNVSKG SPVIQVLAYD ADEGANADVI YSVDSMEDVA
EDLVEINAAT GVVKVKESLV GLENRAFNFK VKAEDGRPPH WNSLVPVNLQ IVPREVTLPR
FSEPLYTFSA SEDLPEGSEI GSVKAFAEDP IIYSLVKGTT TESNKDEVFT LDEQTGALKI
KKAVDHETTK WYQIDVMAHC SHQETELVSL VSVNIQVQDV NDNRPVFEAD PYKAFVMENM
PSGTTVIQVT ANDQDTGSDG QVTYSLEAES GNLRGLFTID GESGWITTLK ELDCEAQEIY
QFYVVATDHG RKVQLSSQTL VEVTVSDEND NAPQFTSDFY KGSVIENAEP GQVVVTLSTI
DADISEQNRR VTCYITEGDV LGQFTVNQIE GEWTISSKKP LDREDTEKYL LKVMASDGKF
QATTEVEIFV LDINDNSPEC GQIFYTGRVS EDALPGLFIL KISATDPDVG SNAQITYSLH
GPGAEEFRLG PHTGELTTSA PLDREQKPTY HLVAKATDGG GRSCQADITL IVEDTNDNAP
RFFPSHCAVA VFDNTTTKTP IAVVAARDLD EGLNAEVVYS LSDSANGHFS IEETTGVIRL
EKPLKDSQHS AFELTVCATD RGSPEPLSAL GTVTVSVVDL TEYLPVFLAP EYVAMVKEDV
AVGTEVLNLS ALTRDNAENT EIKYEIVNGN DHGKFQLNSN TGALYINGSL DFEASHEYYL
SIEGTRKGSA SLSDVTMVVI NITDINDHAP EFIQDPYFAD IREDAAVGEI ILTVSADDLD
GAMNNQITYS IVGGNPLGHF TIQPKSGQIS IAKHLDREEI PSYSLTVRAT DNGHPAQFSD
VAVHVHVSDV NDNPPRFFQL NYSVVVQENA PVGTSVLELI MSDRDTPENG PPYSFQITQG
NDGKAFDVTQ NGLLVTSSIL NRRMKEQYLL QVQVSDSGIP PLSSSAFINI QVTEQSQYAP
SALPLEIFIT TNEEAFRGGV LGKIHATDRD PHDTLVYTLV AEVPQEGLFS VGTADGKIIA
GDKLPHGHYL LNVTVSDGTF TATTSVNVHV WCFTQEALDK AVVLHFRHLS PEEFVGDHWR
NLQRFLGNIL VTRRQNIHMA SLQPAAASDG VDLLLAVGEP HGSLYEPRVL ANKITVSAGE
MDQLVGLRMK KAIHVPCHGP DCIHRVCKET IQLDPGMMST YSTARLSVLT PRHSLEQICS
CNGTAVRFGG HSYIWYQHSQ IGSWHMHFRL KTHQLHAVVF YANGTDHATL EIVNGVPQLG
YSCRGNHTGN LSSSRFVSDG EWHSVFLEVK NTSVRLLIDG LGNASLQLPA TCSISRGRRD
LLFGGLRQPL QSQRVTRGFR GCLDVVAING REVVLLPGKG QSKEVMEEVG IKQCCSPTGA
CSSNPCLNNG MCSETHGGGY TCICPGLFSG ERCELGDSPC ESKPCLHGGT CTLSATGYSC
HCPDWYLGER CEKLAEECQD NPCRNAGRCV SNQGSVHCIC PSDYQGDYCT QPIITPAIVP
TQWTVGPEEI AEIVAGVLGV AILAAAFVLI RKRYRHRAKA HKPVAREDPD LLSKSEFSKS
VGVGTQAVPP IELNILSDAP HNNLDRATPE QRKPTSTPEF VTFNSANAPK HRGTIVCSVA
PNLPPAAPPS NSDNESFVKC TWAREEMVYP AETTYWPPRY LSSDVQEYSH YEIIQGPPAS
SSHPPLPP
//
