ID A0A091UC64_PHORB Unreviewed; 68 AA.
AC A0A091UC64;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Vacuolar protein sorting-associated protein 37C {ECO:0000313|EMBL:KFQ87667.1};
DE Flags: Fragment;
GN ORFNames=N337_06013 {ECO:0000313|EMBL:KFQ87667.1};
OS Phoenicopterus ruber ruber.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Phoenicopteriformes; Phoenicopteridae;
OC Phoenicopterus.
OX NCBI_TaxID=9218 {ECO:0000313|EMBL:KFQ87667.1, ECO:0000313|Proteomes:UP000053700};
RN [1] {ECO:0000313|EMBL:KFQ87667.1, ECO:0000313|Proteomes:UP000053700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N337 {ECO:0000313|EMBL:KFQ87667.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular
CC trafficking process. Required for the sorting of endocytic
CC ubiquitinated cargos into multivesicular bodies. May be involved in
CC cell growth and differentiation. {ECO:0000256|ARBA:ARBA00025010}.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Late endosome membrane
CC {ECO:0000256|ARBA:ARBA00004633}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004633}.
CC -!- SIMILARITY: Belongs to the VPS37 family.
CC {ECO:0000256|ARBA:ARBA00007617}.
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DR EMBL; KK425546; KFQ87667.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091UC64; -.
DR Proteomes; UP000053700; Unassembled WGS sequence.
DR GO; GO:0000813; C:ESCRT I complex; IEA:UniProt.
DR GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009056; P:catabolic process; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.287.660; Helix hairpin bin; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR029012; Helix_hairpin_bin_sf.
DR InterPro; IPR009851; Mod_r.
DR PANTHER; PTHR13678; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37; 1.
DR PANTHER; PTHR13678:SF12; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37D; 1.
DR Pfam; PF07200; Mod_r; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR PROSITE; PS51314; VPS37_C; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000053700};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..68
FT /note="VPS37 C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51314"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ87667.1"
FT NON_TER 68
FT /evidence="ECO:0000313|EMBL:KFQ87667.1"
SQ SEQUENCE 68 AA; 7807 MW; 15FDDA4242E75EAE CRC64;
LEKWSLQSAL GQLQAKLDAS EAESEAQIEQ FLAQDLPLDS FLESFCQSRT RSHICRTQLE
KLQELLQK
//
