ID A0A091UTF8_NIPNI Unreviewed; 178 AA.
AC A0A091UTF8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Protein shisa-9 {ECO:0000313|EMBL:KFQ93981.1};
DE Flags: Fragment;
GN ORFNames=Y956_08759 {ECO:0000313|EMBL:KFQ93981.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFQ93981.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFQ93981.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFQ93981.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Regulator of short-term neuronal synaptic plasticity in the
CC dentate gyrus. Associates with AMPA receptors (ionotropic glutamate
CC receptors) in synaptic spines and promotes AMPA receptor
CC desensitization at excitatory synapses.
CC {ECO:0000256|ARBA:ARBA00037492}.
CC -!- SUBCELLULAR LOCATION: Cell projection, dendritic spine membrane
CC {ECO:0000256|ARBA:ARBA00029429}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00029429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
CC -!- SIMILARITY: Belongs to the shisa family. SHISA9 subfamily.
CC {ECO:0000256|ARBA:ARBA00038448}.
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DR EMBL; KL410116; KFQ93981.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091UTF8; -.
DR STRING; 128390.A0A091UTF8; -.
DR eggNOG; ENOG502QT2A; Eukaryota.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0032591; C:dendritic spine membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR026910; Shisa.
DR PANTHER; PTHR31774:SF1; PROTEIN SHISA-9; 1.
DR PANTHER; PTHR31774; PROTEIN SHISA-9-RELATED; 1.
DR Pfam; PF13908; Shisa; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..178
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001882903"
FT TRANSMEM 143..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ93981.1"
FT NON_TER 178
FT /evidence="ECO:0000313|EMBL:KFQ93981.1"
SQ SEQUENCE 178 AA; 19845 MW; 84C6FF64610E86BE CRC64;
LGGRMEGFIR LLFGYLVADL LTLVCRAQEK AGQQLGSFVV LSGGNHSSLA EQLDPSEPPP
TPDFCRGYFD VMGQWDPPFN CSSGEFIFCC GTCGFRFCCK FKKTRLDQST CTNYETPLWM
NTGKPPSRID DPLHDPTRDK TNLIVYIICG VVAVMVLVGI FTKLGLEKAH RPQREHMS
//
