ID A0A091UYH2_NIPNI Unreviewed; 419 AA.
AC A0A091UYH2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Carboxypeptidase A1 {ECO:0000313|EMBL:KFQ95065.1};
GN ORFNames=Y956_06181 {ECO:0000313|EMBL:KFQ95065.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFQ95065.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFQ95065.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFQ95065.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M14 family.
CC {ECO:0000256|ARBA:ARBA00005988}.
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DR EMBL; KL410244; KFQ95065.1; -; Genomic_DNA.
DR RefSeq; XP_009460867.1; XM_009462592.1.
DR AlphaFoldDB; A0A091UYH2; -.
DR STRING; 128390.A0A091UYH2; -.
DR MEROPS; M14.001; -.
DR GeneID; 104010476; -.
DR KEGG; nni:104010476; -.
DR eggNOG; KOG2650; Eukaryota.
DR OrthoDB; 3540647at2759; -.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd03870; M14_CPA; 1.
DR Gene3D; 3.30.70.340; Metallocarboxypeptidase-like; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR034248; CPA_M14_CPD.
DR InterPro; IPR036990; M14A-like_propep.
DR InterPro; IPR003146; M14A_act_pep.
DR InterPro; IPR000834; Peptidase_M14.
DR PANTHER; PTHR11705:SF117; PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11705; PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B; 1.
DR Pfam; PF00246; Peptidase_M14; 1.
DR Pfam; PF02244; Propep_M14; 1.
DR PRINTS; PR00765; CRBOXYPTASEA.
DR SMART; SM00631; Zn_pept; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00133; CARBOXYPEPT_ZN_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645,
KW ECO:0000313|EMBL:KFQ95065.1};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..419
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001881075"
FT DOMAIN 306..316
FT /note="Peptidase M14 carboxypeptidase A"
FT /evidence="ECO:0000259|PROSITE:PS00133"
SQ SEQUENCE 419 AA; 46951 MW; 0E91C7D39C5992B9 CRC64;
MKILLVFATF VAAACSGQRF VGDQVLRITA SDEEQMALLR VLGEQAELQA DFWRHPTSPG
CPADVRVPFP SLRAVKTFLE SNSISYSIMI EDVQELLDEE KKTMMKSRRA VRSTSTFDFA
SYHTLEEIYD WMDTLVDDHP SLVSKIQIGQ SYENRPLYVL KFSTGGSNRS AIWLDTGIHS
REWITQATGI WTANKIAEGY GQDPSITAIL DSMDIFFEII INPDGFAFTH SSNRMWRKTR
SINAGSHCVG VDPNRNWDAG FGGSGSSSNP CSETYRGPYA HSESEVKAVV DFIRSHGNVK
SVISIHSYSQ MLLFPYGYKR APAPNHQELN ELAKKAVSDL AAVYGTKYTY GSIVDTIYMA
DGTTVDWAYD NGVKYSFTFE LRDTGRYGFL LPSTQIIPTA TETWPALLDI MIHVLEHPY
//
