ID A0A091V0T1_PHORB Unreviewed; 407 AA.
AC A0A091V0T1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 03-MAY-2023, entry version 24.
DE SubName: Full=Rho GTPase-activating protein 42 {ECO:0000313|EMBL:KFQ83408.1};
DE Flags: Fragment;
GN ORFNames=N337_08376 {ECO:0000313|EMBL:KFQ83408.1};
OS Phoenicopterus ruber ruber.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Phoenicopteriformes; Phoenicopteridae;
OC Phoenicopterus.
OX NCBI_TaxID=9218 {ECO:0000313|EMBL:KFQ83408.1, ECO:0000313|Proteomes:UP000053700};
RN [1] {ECO:0000313|EMBL:KFQ83408.1, ECO:0000313|Proteomes:UP000053700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N337 {ECO:0000313|EMBL:KFQ83408.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK408454; KFQ83408.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091V0T1; -.
DR Proteomes; UP000053700; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd12066; SH3_GRAF3; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR047234; GRAF_fam.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12552; OLIGOPHRENIN 1; 1.
DR PANTHER; PTHR12552:SF3; RHO GTPASE-ACTIVATING PROTEIN 42; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053700};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 5..189
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 349..407
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 192..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ83408.1"
FT NON_TER 407
FT /evidence="ECO:0000313|EMBL:KFQ83408.1"
SQ SEQUENCE 407 AA; 44808 MW; 8F78E02C311AD258 CRC64;
LLFVVFLNEA GFNFVRKCIH AVETRGITIL GLYRIGGVNS KVQKLMNTIF SPKSPPDMDI
DMELWDNKTI TSGLKNYLRC LSEPLMTFKL HKDFIVAVKS DDQNYRVEAV HALVHKLPEK
NREMLDILIK HLVKVSLHSQ QNLMTVSNLG VIFGPTLMRA QEETVAAMMN IKFQNIVVEI
LIEHYEKIFH TAPDPNIPLP QPQSRSGSRR TRAICLSTGS RKPKGRYTPC LADPDSDSYS
SSPDSTPMGS IESLSSHSSE QNSTTKCAPP QPREKSGGIP WIASPPSSNG QKSSGLWTTS
PESSSKEDAT KTDVESDCQS VASVTGPENA SPPTDLTKKT SYSLSGLKRA SAQAKAMYSC
KAEHSHELSF PQGAIFSNVY PSVEPGWLKA TYEGKTGLVP ENYVVFL
//
