ID A0A091V696_NIPNI Unreviewed; 230 AA.
AC A0A091V696;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 7 {ECO:0000256|RuleBase:RU364060};
GN ORFNames=Y956_02384 {ECO:0000313|EMBL:KFQ98593.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFQ98593.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFQ98593.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFQ98593.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. Mediator is recruited to promoters by direct
CC interactions with regulatory proteins and serves as a scaffold for the
CC assembly of a functional preinitiation complex with RNA polymerase II
CC and the general transcription factors. {ECO:0000256|ARBA:ARBA00025687}.
CC -!- SUBUNIT: Component of the Mediator complex.
CC {ECO:0000256|RuleBase:RU364060}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364060}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 7 family.
CC {ECO:0000256|ARBA:ARBA00009994, ECO:0000256|RuleBase:RU364060}.
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DR EMBL; KL410715; KFQ98593.1; -; Genomic_DNA.
DR RefSeq; XP_009465120.1; XM_009466845.1.
DR AlphaFoldDB; A0A091V696; -.
DR STRING; 128390.A0A091V696; -.
DR GeneID; 104014225; -.
DR KEGG; nni:104014225; -.
DR CTD; 9443; -.
DR eggNOG; KOG0570; Eukaryota.
DR OrthoDB; 11599at2759; -.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.140.200; -; 1.
DR InterPro; IPR037212; Med7/Med21-like.
DR InterPro; IPR009244; Mediatior_Med7.
DR InterPro; IPR044888; Mediatior_Med7_sf.
DR PANTHER; PTHR15498:SF72; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7; 1.
DR PANTHER; PTHR15498; T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING TIM; 1.
DR Pfam; PF05983; Med7; 1.
DR SUPFAM; SSF140718; Mediator hinge subcomplex-like; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU364060};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364060};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW Transcription {ECO:0000256|RuleBase:RU364060};
KW Transcription regulation {ECO:0000256|RuleBase:RU364060}.
SQ SEQUENCE 230 AA; 26712 MW; 1E600E5E28E90FA4 CRC64;
MGEPQQVSAL PPPPMQYIKE YTDENIRKGL APKPPPPVKD SYMMFGNQFQ CDDLIIRPLE
SQGIERLHPM QFDHKKELRK LNMSILVNFL DLLDILIRSP GSIKREEKLE DLKLLFVHVH
HLINEYRPHQ ARETLRVMME VQKRQRLETA ERFQKHLERV VEMIQNCLAS LPDDLPHSEG
GLRVKVETMD TDDGSNCIGQ SEKQRERSCG KRDQVLDKDA AMCSIIDEMT
//
