ID   A0A091V8I6_NIPNI        Unreviewed;       655 AA.
AC   A0A091V8I6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Protein artemis {ECO:0000256|ARBA:ARBA00039759};
DE   AltName: Full=DNA cross-link repair 1C protein {ECO:0000256|ARBA:ARBA00042677};
DE   Flags: Fragment;
GN   ORFNames=Y956_03935 {ECO:0000313|EMBL:KFQ99104.1};
OS   Nipponia nippon (Crested ibis) (Ibis nippon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC   Nipponia.
OX   NCBI_TaxID=128390 {ECO:0000313|EMBL:KFQ99104.1, ECO:0000313|Proteomes:UP000053283};
RN   [1] {ECO:0000313|EMBL:KFQ99104.1, ECO:0000313|Proteomes:UP000053283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFQ99104.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC       family. {ECO:0000256|ARBA:ARBA00010304}.
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DR   EMBL; KL410746; KFQ99104.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091V8I6; -.
DR   STRING; 128390.A0A091V8I6; -.
DR   eggNOG; KOG1361; Eukaryota.
DR   Proteomes; UP000053283; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.12650; -; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR011084; DRMBL.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR   PANTHER; PTHR23240:SF38; PROTEIN ARTEMIS; 1.
DR   Pfam; PF07522; DRMBL; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053283}.
FT   DOMAIN          187..290
FT                   /note="DNA repair metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|Pfam:PF07522"
FT   REGION          326..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          461..568
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          584..633
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..387
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        397..416
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        424..440
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..531
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        598..619
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFQ99104.1"
FT   NON_TER         655
FT                   /evidence="ECO:0000313|EMBL:KFQ99104.1"
SQ   SEQUENCE   655 AA;  73336 MW;  6DFB9AC890CD8667 CRC64;
     SLKVKLYCSP VTKELLLTSW KYKFWENHIV ALEVETPTQI SLVDETSGEK EDLEVTLLPA
     GHCPGSVMFL FEGANGTVLY TGDFRLAKGE AARMELLHSG TRVKDIQSVY LDTTFCDPKF
     YHIPSREECL NGILELVRSW TSLTRYHVVW LNCKAAYGYE YLFINLSEEL GIKVHVNKLD
     MFRNMPEILY HVTTDRHTQI HACRHPRDDD CFRGNRLPCG MTCQNGTPLR IISIKPSTMW
     FGERIKKTSV IVRTGESTYR ACFSFHSSYS EIKDFLSYIR PVNVYPNVLP VGGTEEKVME
     ILKPLCRSYR RNMEPRYKPL GTLKRVHKRD LSDTDEDDLF DSELASARPK IPKQQREESM
     PAGTGQSENA DGNVNESTES YKATTTYASP KVDFVDCEES NDDDDDEDDE EEESEINAVQ
     VLSHEPDAPS TSNFSGVTRD QQEPDADVLR WDAFFKCNKL EESSENEDTF PSSADAGGSQ
     SLFSDSDAVS DSTHISSQNS SQSTHISEQG SQGWDSQSDT VLITSQERNA LDSGCLGKGG
     SRAVVSALPE AAKDSRPDSS RGKPVGQNRS CAYGVACELK SKDCETDAEA GTARGQDVQV
     EIRDDSRTPE RELRRDSQSS SDFEIPLTPD AEVPRPDKLY CLYKKLAAGE SILNE
//