ID   A0A091VG73_NIPNI        Unreviewed;       329 AA.
AC   A0A091VG73;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Adenosine deaminase-like {ECO:0000313|EMBL:KFR02144.1};
DE   Flags: Fragment;
GN   ORFNames=Y956_05548 {ECO:0000313|EMBL:KFR02144.1};
OS   Nipponia nippon (Crested ibis) (Ibis nippon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC   Nipponia.
OX   NCBI_TaxID=128390 {ECO:0000313|EMBL:KFR02144.1, ECO:0000313|Proteomes:UP000053283};
RN   [1] {ECO:0000313|EMBL:KFR02144.1, ECO:0000313|Proteomes:UP000053283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFR02144.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + H2O + N(6)-methyl-AMP = IMP + methylamine;
CC         Xref=Rhea:RHEA:16001, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:58053, ChEBI:CHEBI:59338, ChEBI:CHEBI:144842;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16002;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
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DR   EMBL; KL411005; KFR02144.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091VG73; -.
DR   STRING; 128390.A0A091VG73; -.
DR   eggNOG; KOG1097; Eukaryota.
DR   Proteomes; UP000053283; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   CDD; cd00443; ADA_AMPD; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF42; ADENOSINE DEAMINASE-LIKE PROTEIN; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053283}.
FT   DOMAIN          1..323
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFR02144.1"
FT   NON_TER         329
FT                   /evidence="ECO:0000313|EMBL:KFR02144.1"
SQ   SEQUENCE   329 AA;  37077 MW;  2896244E55132AE4 CRC64;
     ELHAHLNGCI SSATMKKLMA QKPYLQIQNG MTVIDKGKKR TLDECFQMFQ IIYQITTRTE
     DILLITKDVI KEFADDGVKY LELRSTPREE KSTGMTKRMY VETVLEGIKQ CKEEGLDIDV
     RLLIAINRRG GPAVAKQTVK LAEEFLLSTD GVVVGLDLSG DPTVRHGQDF LEPLSEAKKA
     GLKLALHLSE IPNQEEETKI LLGLPPDRIG HGTFLNSATT GSEELVPLVR QNHIPIELCM
     TSNIKTQTVP SCDKHHFGYW YNMGHPAVLC TDDKGVFATD LSQEYELVAE TFNLTRSQMW
     DLSYESINYI FASSVVKSKL REQWCKLKP
//