ID A0A091VR60_NIPNI Unreviewed; 683 AA.
AC A0A091VR60;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Neuronal PAS domain-containing protein 2 {ECO:0000313|EMBL:KFR05210.1};
DE Flags: Fragment;
GN ORFNames=Y956_02424 {ECO:0000313|EMBL:KFR05210.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFR05210.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFR05210.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFR05210.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL411262; KFR05210.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091VR60; -.
DR STRING; 128390.A0A091VR60; -.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0032922; P:circadian regulation of gene expression; IEA:InterPro.
DR CDD; cd19736; bHLH-PAS_PASD1; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR047230; CLOCK-like.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR PANTHER; PTHR46055:SF4; CIRCADIAN CLOCK PROTEIN PASD1; 1.
DR PANTHER; PTHR46055; CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Biological rhythms {ECO:0000256|ARBA:ARBA00023108};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 10..62
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 85..148
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 263..310
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 663..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 509..543
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 392..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFR05210.1"
FT NON_TER 683
FT /evidence="ECO:0000313|EMBL:KFR05210.1"
SQ SEQUENCE 683 AA; 77379 MW; C77A96FFED66B2D9 CRC64;
LMDEDEKDRA KRASRNKSEK KRRDQFNVLI KELCTMLQGH GHPLKMDKST ILQRTIDFLQ
KQKEITAQTE ACEIRQDWKP SFLSNEEFTQ LMLEALDGFL IALTTDGIII YVSDSVSSLL
GHLPSDLVDQ NILNFLPERE QSEVYKLLSP HVLMTDPIAA DFLNAEKQIE FCCHLARGSL
DPNEPLMYEY VKFVVDFKYF THVPTPSCNG FESAIARAFR SATEEQICLV ATVRLVTPQF
LKELCNVEEP CEEFTSRHSL EWKFLFLDHR APPIIGYLPF EVLGTSGYDY YHADDLELLA
RCHEHLMQFG KGKSCYYRFL TKGQQWIWLQ THYYITYHQW NSKPEFIVCT HLVVSYAEVR
AERRRDLGLE ESSIELASSS LKSHSSYLDV GQCSSSQDAS REGVSLSSHS SRRSSHTALS
DSACRCQSTS STRHTDTSTP TRSSVPGGQA EKAALRLASS GSTQAIATPQ APGEHLPQHP
VAQPAVPSQH TVMPVYHFPT QLGMMHQLKE QLEERTRILQ ADIKTQQEEL HVIKEQLQLV
QDSNLQMLMQ QPIPVVFNNV QHPIPRRPPP PPGTPRQTTA KKSQQQGLLG MKHYCGTHLP
SPRQFLRDPC GTAAQVQQQQ QHLMRGNQAQ QTCLLGQTSI SVPLYNNPMV FSQTHPITVA
AQMPTDGGER QPQPDYGQDR SLR
//
