ID   A0A091VS72_NIPNI        Unreviewed;       306 AA.
AC   A0A091VS72;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Epidermal retinol dehydrogenase 2 {ECO:0000313|EMBL:KFR06237.1};
DE   Flags: Fragment;
GN   ORFNames=Y956_15582 {ECO:0000313|EMBL:KFR06237.1};
OS   Nipponia nippon (Crested ibis) (Ibis nippon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC   Nipponia.
OX   NCBI_TaxID=128390 {ECO:0000313|EMBL:KFR06237.1, ECO:0000313|Proteomes:UP000053283};
RN   [1] {ECO:0000313|EMBL:KFR06237.1, ECO:0000313|Proteomes:UP000053283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFR06237.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|RuleBase:RU000363}.
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DR   EMBL; KL411364; KFR06237.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091VS72; -.
DR   STRING; 128390.A0A091VS72; -.
DR   eggNOG; KOG1201; Eukaryota.
DR   Proteomes; UP000053283; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05339; 17beta-HSDXI-like_SDR_c; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR24322; PKSB; 1.
DR   PANTHER; PTHR24322:SF751; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 16C MEMBER 5; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        259..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFR06237.1"
FT   NON_TER         306
FT                   /evidence="ECO:0000313|EMBL:KFR06237.1"
SQ   SEQUENCE   306 AA;  34203 MW;  940CAC4CBA5F92CB CRC64;
     FRSILKLLQL LKLLFFLFFD NFILFIFPPC KKTFAGVIML ITGSANGIGR QIALKFAPLG
     ATLVLWDIDD EGNKETSRLA GKIGAQRVFA YHCDCSNRQE VYEQADKVRK EVGDVTILIN
     NAGILIGKKF CDTPDADFEK TLRVNFLSQV WTCKAFLPAM MTCNRGHLVS IASVAALLGT
     YRMSDYTASK CAIIGMMEAL DSELYHAGKQ GIKTTIICLS IVNTELAKGV QTPNHLLLPV
     YEAEYVASKI MDAIQKEKFY LIMPLILHLL AFKIVCLISL IPRKMILLFE SCLKITNILD
     KGFGRK
//