ID   A0A091VT78_OPIHO        Unreviewed;       168 AA.
AC   A0A091VT78;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Interleukin family protein {ECO:0000256|RuleBase:RU368043};
DE   Flags: Fragment;
GN   ORFNames=N306_04375 {ECO:0000313|EMBL:KFR06602.1};
OS   Opisthocomus hoazin (Hoatzin) (Phasianus hoazin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae;
OC   Opisthocomus.
OX   NCBI_TaxID=30419 {ECO:0000313|EMBL:KFR06602.1, ECO:0000313|Proteomes:UP000053605};
RN   [1] {ECO:0000313|EMBL:KFR06602.1, ECO:0000313|Proteomes:UP000053605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N306 {ECO:0000313|EMBL:KFR06602.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Immune regulatory cytokine. {ECO:0000256|RuleBase:RU368043}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC       ECO:0000256|RuleBase:RU368043}.
CC   -!- SIMILARITY: Belongs to the IL-10 family.
CC       {ECO:0000256|ARBA:ARBA00008813, ECO:0000256|RuleBase:RU368043}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KK734346; KFR06602.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091VT78; -.
DR   STRING; 30419.A0A091VT78; -.
DR   PhylomeDB; A0A091VT78; -.
DR   Proteomes; UP000053605; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-UniRule.
DR   GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.10; -; 1.
DR   InterPro; IPR009079; 4_helix_cytokine-like_core.
DR   InterPro; IPR020443; IL-10/19/20/22/24/26_fam.
DR   PANTHER; PTHR48394; INTERLEUKIN-19-RELATED; 1.
DR   PANTHER; PTHR48394:SF2; INTERLEUKIN-26; 1.
DR   Pfam; PF00726; IL10; 1.
DR   SUPFAM; SSF47266; 4-helical cytokines; 1.
PE   3: Inferred from homology;
KW   Cytokine {ECO:0000256|ARBA:ARBA00022514, ECO:0000256|RuleBase:RU368043};
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR620443-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053605};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525, ECO:0000256|RuleBase:RU368043};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU368043}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|RuleBase:RU368043"
FT   CHAIN           24..168
FT                   /note="Interleukin family protein"
FT                   /evidence="ECO:0000256|RuleBase:RU368043"
FT                   /id="PRO_5031600375"
FT   DISULFID        33..120
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620443-50"
FT   DISULFID        79..123
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620443-50"
FT   NON_TER         168
FT                   /evidence="ECO:0000313|EMBL:KFR06602.1"
SQ   SEQUENCE   168 AA;  18914 MW;  5CD09D42EA025A48 CRC64;
     MKVDPIFRSG RFLVLLCLFT VEGKKSPTGK HTCRKGLLSQ VTENLYIKAT SLKSSVPKDL
     IKNTRLLEKT TKMLFMTNCS VRDQLLSFYV KNVFSHPGVG SDKLYIISAF QVLQANMNAC
     LPCAPSTRLT SAVKKLKKTF LKLGEKGIYK AIHELDILLP WIQAYIQT
//