ID A0A091WA98_OPIHO Unreviewed; 795 AA.
AC A0A091WA98;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Follistatin-related protein 5 {ECO:0000313|EMBL:KFR12597.1};
DE Flags: Fragment;
GN ORFNames=N306_02770 {ECO:0000313|EMBL:KFR12597.1};
OS Opisthocomus hoazin (Hoatzin) (Phasianus hoazin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae;
OC Opisthocomus.
OX NCBI_TaxID=30419 {ECO:0000313|EMBL:KFR12597.1, ECO:0000313|Proteomes:UP000053605};
RN [1] {ECO:0000313|EMBL:KFR12597.1, ECO:0000313|Proteomes:UP000053605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N306 {ECO:0000313|EMBL:KFR12597.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; KK735119; KFR12597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091WA98; -.
DR STRING; 30419.A0A091WA98; -.
DR PhylomeDB; A0A091WA98; -.
DR Proteomes; UP000053605; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05736; IgI_2_Follistatin_like; 1.
DR CDD; cd00104; KAZAL_FS; 1.
DR Gene3D; 3.30.60.30; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR10913; FOLLISTATIN-RELATED; 1.
DR PANTHER; PTHR10913:SF44; FOLLISTATIN-RELATED PROTEIN 5; 1.
DR Pfam; PF13927; Ig_3; 2.
DR Pfam; PF07648; Kazal_2; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF75011; 3-carboxy-cis,cis-mucoante lactonizing enzyme; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053605};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 37..84
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT DOMAIN 124..159
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 199..287
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 290..375
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFR12597.1"
FT NON_TER 795
FT /evidence="ECO:0000313|EMBL:KFR12597.1"
SQ SEQUENCE 795 AA; 89592 MW; 16E8D0D7891BECA8 CRC64;
ISGYVGQDGQ FGSCENKYCG LGRHCVENGE TGQAECLCME QCKPHYKPVC GSDGEFYKNH
CEVHRTACLK KQKVTIVHNE DCFFKGDKCK PTEYTKVKNM LLDLQNRRYI AQSKDKTVGE
KMALKKLLVD QMFNYFDSDN NGLVDTSELS QVIKRDELGK DLSDCSLFDL LKYDDYNSDK
HLALEEFYRA FQVVQLSLPE DQKLSTTAAT VGQSAVLSCA IQGILRPPIV WKRNNVILNS
LDLEDINDFG DDGSLYITKV TTTHMGNYTC YADGYDKLYQ THTLQVNVPP VIRVYPESQA
REPGVTASLR CHAEGIPNPQ LAWLKNGIDI TPKLSKQLTL QANGSEVHIS NVRYEDTGAY
TCIAKNEAGV DEDISSLFVE DSARKTLANI LWREQGTNRW LFSYFLCYDE MLMYLHFWVF
FVVHVLQIIS MDPQDEVCPI ADGDPVQRCV WATAVNVKDK FIYVAQPTLD RILIVDVQSQ
KVVQAVSTDP VPVKLHYDKS HDQVWVLSWG NMEKNSPTLQ VITQASVSVS HHTIHTQPVG
RQFDRVDDFF IPAATLIITH IRFGFILHKD EPVLQKIDLE TMSYIKTISL KDYSCIPQSL
AYTHLGGYFF ICCKPDTTGA VLPQLIVDSV TDSVIGYNGD ITGTPRISPD GHYLVSIDDA
KGLMRIQSIT MRGEIQDAFD IHTNLHISDV AFQPSFTEAH QYNVYCSSST QTDVLFVELS
SGKVKMVKSL KEPVKAGEWP WNSKNRLITD SGLFGQYLMT PSKESLFILD GRLNKLNCEI
TEVERGNTVI WVGEA
//
