ID A0A091WF18_OPIHO Unreviewed; 610 AA.
AC A0A091WF18;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Voltage-dependent L-type calcium channel subunit beta-2 {ECO:0000256|ARBA:ARBA00019005};
DE AltName: Full=Calcium channel voltage-dependent subunit beta 2 {ECO:0000256|ARBA:ARBA00030521};
GN ORFNames=N306_12580 {ECO:0000313|EMBL:KFR13388.1};
OS Opisthocomus hoazin (Hoatzin) (Phasianus hoazin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae;
OC Opisthocomus.
OX NCBI_TaxID=30419 {ECO:0000313|EMBL:KFR13388.1, ECO:0000313|Proteomes:UP000053605};
RN [1] {ECO:0000313|EMBL:KFR13388.1, ECO:0000313|Proteomes:UP000053605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N306 {ECO:0000313|EMBL:KFR13388.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004278}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004278}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004278}.
CC -!- SIMILARITY: Belongs to the calcium channel beta subunit family.
CC {ECO:0000256|ARBA:ARBA00010836}.
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DR EMBL; KK735254; KFR13388.1; -; Genomic_DNA.
DR RefSeq; XP_009936211.1; XM_009937909.1.
DR AlphaFoldDB; A0A091WF18; -.
DR STRING; 30419.A0A091WF18; -.
DR GeneID; 104332497; -.
DR KEGG; oha:104332497; -.
DR CTD; 783; -.
DR OrthoDB; 2953516at2759; -.
DR PhylomeDB; A0A091WF18; -.
DR Proteomes; UP000053605; Unassembled WGS sequence.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR CDD; cd12040; SH3_CACNB2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046937; CAB1-4_N_A-dom.
DR InterPro; IPR035605; CACNB2_SH3.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR005444; VDCC_L_b2su.
DR InterPro; IPR000584; VDCC_L_bsu.
DR PANTHER; PTHR11824; VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT; 1.
DR PANTHER; PTHR11824:SF9; VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT BETA-2; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF12052; VGCC_beta4Aa_N; 1.
DR PRINTS; PR01626; LCACHANNELB.
DR PRINTS; PR01628; LCACHANNELB2.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Calcium channel {ECO:0000256|ARBA:ARBA00022673};
KW Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053605};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT DOMAIN 66..135
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 24..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..455
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..610
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 68908 MW; 651F651F9F815C23 CRC64;
MKATWIRLLK RAKGGRLKNS DICGSADSYT SRPSDSDVSL EEDREAVRRE AERQAQAQLE
KAKTKPVAFA VRTNVGYSAA HDDDVPVPGM AISFEAKDFL HVKEKFNNDW WIGRLVKEGC
EIGFIPSPVK LENMRLQHEQ KAKQGKFYSS KSGGNSSSSL GDIVPSSRKS TPPSSAIDID
ATGLDAEEND IPANHRSPKP SANSVTSPHS KEKRMPFFKK TEHIPPYDVV PSMRPVVLVG
PSLKGYEVTD MMQKALFDFL KHRFEGRISI TRVTADISLA KRSVLNNPSK HAIIERSNTR
SSLAEVQSEI ERIFELARTL QLVVLDADTI NHPAQLSKTS LAPIIVYVKI SSPKVLQRLI
KSRGKSQAKH LNVQMVAADK LAQCPPEMFD VILDENQLED ACEHLADYLE AYWKATHPPS
SNPPNQLLTR TLAPATLPIS PGPNINLQGS QGDQRNDHSV PERSGSQIEE EARVEPIKKS
QHRSSSSQHH NHRSGVRGLS RQETFDSETQ DSRDSAYVEP KEDYSHEHGD HYDSHRDHNH
RDESHGSSDH RHRESRHRSK ERDREQDHNE CNKQRSRHKS RDQYCDKDGE VISKKRNDTG
EWNRDVYIRQ
//
