ID A0A091WNE0_NIPNI Unreviewed; 3726 AA.
AC A0A091WNE0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Ankyrin-2 {ECO:0000313|EMBL:KFR03041.1};
DE Flags: Fragment;
GN ORFNames=Y956_11996 {ECO:0000313|EMBL:KFR03041.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFR03041.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFR03041.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFR03041.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR EMBL; KL411059; KFR03041.1; -; Genomic_DNA.
DR STRING; 128390.A0A091WNE0; -.
DR eggNOG; KOG4177; Eukaryota.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08804; Death_ank2; 1.
DR Gene3D; 2.60.220.30; -; 2.
DR Gene3D; 2.60.40.2660; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR040745; Ankyrin_UPA.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR24123:SF49; ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING 1B; 1.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF00023; Ank; 3.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF13637; Ank_4; 3.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF17809; UPA_2; 1.
DR Pfam; PF00791; ZU5; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 23.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00218; ZU5; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 20.
DR PROSITE; PS50088; ANK_REPEAT; 20.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS51145; ZU5; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 36..68
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 69..101
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 102..134
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 205..237
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 238..270
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 271..303
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 304..336
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 337..369
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 370..402
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 403..435
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 436..468
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 469..501
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 502..534
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 535..567
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 568..600
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 601..633
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 634..666
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 667..699
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 700..732
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 733..765
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 941..1096
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1098..1244
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 3343..3427
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 1606..1684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1711..1918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1982..2152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2183..2343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2360..2469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2499..2547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2594..2638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2748..2775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2823..2860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2886..3022
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3077..3115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3131..3233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3322..3343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3461..3666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3688..3707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1629..1657
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1778..1794
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1796..1854
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1879..1908
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2059..2152
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2270..2314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2329..2343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2360..2377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2448..2462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2503..2517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2530..2547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2594..2614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2755..2771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2830..2855
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2898..2912
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3077..3093
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3153..3206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3217..3232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3462..3487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3494..3508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3544..3569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3627..3646
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFR03041.1"
FT NON_TER 3726
FT /evidence="ECO:0000313|EMBL:KFR03041.1"
SQ SEQUENCE 3726 AA; 409572 MW; B0AE29749B74EB04 CRC64;
QSDSNASFLR AARAGNLDKV VEYLKSGIDI NTCNQNGLNA LHLAAKEGHV GLVQELLERG
SAVDSATKKG NTALHIASLA GQAEVVKVLV KEGANINAQS QNGFTPLYMA AQENHIEVVK
YLLENGANQS TATEDGFTPL AVALQQGHNQ AVAILLENDT KGKVRLPALH IAARKDDTKS
AALLLQNDHN ADVQSKVTRC CRRGSGFTPL HIAAHYGNVN VATLLLNRGA AVDFTARNGI
TPLHVASKRG NTNMVKLLLD RGGQIDAKTR DGLTPLHCAA RSGHDQVVEL LLERGAPLLA
RTKNGLSPLH MAAQGDHVEC VKHLLQHKAP VDDVTLDYLT ALHVAAHCGH YRVTKLLLDK
RANPNARALN GFTPLHIACK KNRIKVMELL VKYGASIQAI TESGLTPIHV AAFMGHLNIV
LLLLQNGASP DVTNIRGETA LHMAARAGQV EVVRCLLRNG ALVDARAREE QTPLHIASRL
GKTEIVQLLL QHMAHPDAAT TNGYTPLHIS AREGQVDVAS VLLEAGASHS MSTKKGFTPL
HVAAKYGSLE VAKLLLQRRA SPDSAGKNGL TPLHVAAHYD NQKVALLLLE KGASPHSTAK
NGYTPLHIAA KKNQMQIATT LLNYGAETNI LTKQGVTPLH LASQEGHADM VTLLLEKGSN
IHVATKTGLT SLHLAAQEDK VNVAEILTKH GANQDAQTKL GYTPLIVACH YGNIKMVNFL
LKQGANVNAK TKNGYTPLHQ AAQQGHTHII NVLLQHGAKP NATTTNGNTA LAIARRLGYI
SVVDTLKVVT EEITTTTTTV TEKHKLNVPE TMTEVLDVSD EEGDDTMTGD GGEYLRPEDL
RELGDDSLPS SQFLDGMNYL RYSLEGGRSD SLRSFSSDRS HTLSHASYLR DSAMIDDTVV
IPSQQVTTLA KEAERNSYRL SWGPENLDNV TLSSSPIHSG FLVSFMVDAR GGAMRGCRHN
GLRIIIPPRK CTAPTRVTCR LVKRHRLATM PPMVEGEGLA SRLIEVGPSG AQFLGPVIVE
IPHFAALRGK ERELVILRSE NGDSWKEHFC EYTEDELNEI LNGMDEVLDT PEELEKKRIC
RIITRDFPQY FAVVSRIKQD SNLIGPEGGV LSSTVVPQVQ AVFPEGALTK RIRVGLQAQP
MHTELIKKIL GNKATFSPIV TLEPRRRKFH KPITMTIPVP KASSDGIMNG YGGDTPTLRL
LCSITGGTTP AQWEDITGTT PLTFVNECVS FTTNVSARFW LIDCRQTQES VTFASQVYRE
IICVPYMAKF VVFAKSHDPI EARLRCFCMT DDKVDKTLEQ QENFAEVARS RDVEVLEGKP
IYVDCFGNLV PLTKSGQHHI FSFFAFKENR LPLFVKVRDT TQEPCGRLSF MKEPKSTRGL
VHQAICNLNI TLPVYTKVLP DYIFQSLFLI SILLSMFFVR IKDDETESTE TSILKSHLVN
EVPVLASPDL LSEVSEMKQD LIKMTAILTT DPSDKSGSIK VKDLGKPTEE EPGELNEILR
GGSYTREEHV LQKSLSKQEL VEEEWVIVSD EEIEEARRNA PLEVTEPTCV EVRVGEGMTK
LEKPDMTGVV DYLTEDLKTY VSLHEVQPQA LQEDLVEERF EAVVISRDSE KERQESPTTE
TLSPQEQHKP ALEIKKPVRT KLRDKQKQKE GKMHSSEEQP GLTKLTSDES LGEEPGLTLT
AAPEAKAVSP VIEETPIGSI KDKVKALQKR VEDEQKIRSK LPVRIQTREG TAEKASKRPA
QVKKPVAHKA QPPVSPSSKT ERLEETMSVR ELMKAFQSGQ DPSKNISGLF EHKSVKQKQQ
LPEKETTRRK TTPSQSETRR VSSHKTDKPK DKQSTILKAE KEPQSKKGKM HISTVEITKK
AVGKEQVKEQ SSKKPTEPLP PVFDDESAKD TAVVKGRTSD DQGDTDFQIS PDRKTSTDFS
DVIKEELEDN DKYQQFRHLS VTEEGELNLE QVLTSPFSVA FPTEYVKDGF LPALSLQSAA
FDGSSESLKH EGVADSPGSL LDGTPQISSE ESYKHEGLAE TPETSPESLS FSPKKTDGQI
EEAKGAARAH TTAETCSPKE LSPKEDEKGI TERQLDAVTE TSKSHSDHVS EELVPTASEE
EADKLKESSS ASIMEDISRD KESRTTAHLT KSSETHDTAL EKEKDITCER RVVVRSPQKL
ELSLASHDSE SFSPVADDSL AVSHKDSLEA SPVLEDNSSH KTPDSLEPSP MKESPCRDSL
ESSPVEQTVK AGILGQGPLQ SVLSKGETCP ELASVRSRIL RDPEGSADDD SLEQTSLMES
SGKSPLSPET PSSEEISYEI TPKTADSQAL SSIPKSAMIP EVNEEPEDDS ESEPKKRFTP
EEEMFKMVTK IKMFDELEQE AKQKRDYKKD CKQDESSLVA DSEAACEAEE PESTAAEEKD
IPTVVMPAAE SRKSSSSSES EPELTQLKKE AGSGLLMEPV IRVQPPSPLP SSIDSSSSPD
EAGFQPIDAK QCSIRIGAVK AEQDKLTDDD KEEPLILEGS CKASTRESGT CHSDGCVSAE
TDESKCGSTD DSETVSPSAP VTQSGGTLCH SIGDSSLKEI HVGSSLTLQQ YDTTEKDVDA
TALLTRTDLV STGAVSEKAG DSSCGHSTTG CSVPQDGKLA EDDTTDHSAL GSDLGKADTD
FETSQRDIHA EEPLPEYSSL TTGTVELESG VADAAESSAP YIVSPYENVS SEHFFTDSES
RVGSSRSLLS RENYSIEEGK DQTGEALLSR DTGSECHSSE EVYMEIEPKP EDEFQKMSQG
SSASDSTNLA ESALGDIRDE TEKLISQVVI TKTDVDSDMW SEIREDDEAF EARVKEEEQK
IFGLMVDRRS QGTTPDTTPA RTPTEEGTPL SEQNPFLFQE GKLFEMTRSG AIDMTKRNYP
DESVHFFQMG QQPQEEVSLS EEVKEAAEVE SSKLKSSPDP FLPSESEDSD IQEKDTLKCS
PPASESSDKS EEMTGEGVSV GTTKADLKSR IPIKMGISAS SKSPKKETAA SEAEPLSRTE
TDMVDSSQVP CPISPERSVV EDELDFSKVT RLVCSEQGDE SPDSSPEEQR SVIEIPTALM
ETVPSCESKS KIPVRTAAAA SQCSQQSEDE SLPTDGFLDS LQCEGKDDQA KPKSKIPVKA
AFQKAEQQYT YADASVRKLE SPKALDMTSK LPMKQDNRSK SESDASIPMD PKTKRSIKAR
SYAEAEAETR EREREMKLEL DSDEATTGRP KVFSSRLPVK SRSTTASRSA FSPTKESKEH
FFDLYKNSIE FFEEISDEAS KLVERLTQSE REQELVSDDE SSSALEVSVI ENVPSSETQQ
SVPEDIFDTR PIWDESVETQ IERIPDENVH DHAEDQQDDQ ERTEERLAHI ADHLGFSWTE
LARELDFTEE QIHQIRIENP NSLQDQSHAL LKYWLERDGK HATDTNLTQC LTKINRMDIV
HLMETSGIDS MQVHGTRTYA EIEQTIGLDH SEGFSALQEE VYSSRHKQEE QHRLLSKDSE
PTEHPPIVSE EDVSVSYSPF QDSTPRSEAE VSMAELLRQP QKEQVEAEFS GKPQAVPEET
SAPQREYFVT SPGTEQSTAP VTGKAASERS AHSSAAKEER EKPSPQPPSS AQRGDSPIIQ
EPEDLQLHQD DLSPRRTSLV IVESTDEQTE KFGRGYEEES LEKADSMPEM PPETVTEEQY
TDEHGHTVVK KVTRKIIRRY VSPDGTEKEE VLMQGTPQNP VTVEEGDGYS KVVKRVVLKS
DSEQSE
//
