ID A0A091WP30_OPIHO Unreviewed; 349 AA.
AC A0A091WP30;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=glycogenin glucosyltransferase {ECO:0000256|ARBA:ARBA00038934};
DE EC=2.4.1.186 {ECO:0000256|ARBA:ARBA00038934};
DE Flags: Fragment;
GN ORFNames=N306_10268 {ECO:0000313|EMBL:KFR16870.1};
OS Opisthocomus hoazin (Hoatzin) (Phasianus hoazin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae;
OC Opisthocomus.
OX NCBI_TaxID=30419 {ECO:0000313|EMBL:KFR16870.1, ECO:0000313|Proteomes:UP000053605};
RN [1] {ECO:0000313|EMBL:KFR16870.1, ECO:0000313|Proteomes:UP000053605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N306 {ECO:0000313|EMBL:KFR16870.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Glycogenin participates in the glycogen biosynthetic process
CC along with glycogen synthase and glycogen branching enzyme. It self-
CC glucosylates, via an inter-subunit mechanism, to form an
CC oligosaccharide primer that serves as substrate for glycogen synthase.
CC {ECO:0000256|ARBA:ARBA00043853}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = alpha-D-
CC glucosyl-L-tyrosyl-[glycogenin] + H(+) + UDP; Xref=Rhea:RHEA:23360,
CC Rhea:RHEA-COMP:14604, Rhea:RHEA-COMP:14605, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:46858, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885,
CC ChEBI:CHEBI:140573; EC=2.4.1.186;
CC Evidence={ECO:0000256|ARBA:ARBA00043655};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:23361;
CC Evidence={ECO:0000256|ARBA:ARBA00043655};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-
CC D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + H(+)
CC + UDP; Xref=Rhea:RHEA:56560, Rhea:RHEA-COMP:14606, Rhea:RHEA-
CC COMP:14607, ChEBI:CHEBI:15378, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885,
CC ChEBI:CHEBI:140574; EC=2.4.1.186;
CC Evidence={ECO:0000256|ARBA:ARBA00043795};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:56561;
CC Evidence={ECO:0000256|ARBA:ARBA00043795};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004964}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. Glycogenin
CC subfamily. {ECO:0000256|ARBA:ARBA00038162}.
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DR EMBL; KK736027; KFR16870.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091WP30; -.
DR STRING; 30419.A0A091WP30; -.
DR PhylomeDB; A0A091WP30; -.
DR Proteomes; UP000053605; Unassembled WGS sequence.
DR GO; GO:0008466; F:glycogenin glucosyltransferase activity; IEA:UniProt.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd02537; GT8_Glycogenin; 1.
DR InterPro; IPR002495; Glyco_trans_8.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR11183; GLYCOGENIN SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11183:SF164; GLYCOGENIN-1; 1.
DR Pfam; PF01501; Glyco_transf_8; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis {ECO:0000256|ARBA:ARBA00023056};
KW Reference proteome {ECO:0000313|Proteomes:UP000053605}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFR16870.1"
FT NON_TER 349
FT /evidence="ECO:0000313|EMBL:KFR16870.1"
SQ SEQUENCE 349 AA; 39175 MW; 477C1459CB357FD1 CRC64;
LPDQSFVTLA TNDSYVKGAL VLGSSLQQYR TTRKLTALIT PQVSDPMRRV LEKVFDEVIL
VNILDSGDSA HLALMKRPEL GVTLTKLHCW ELTQFSKCVF MDADTMVLSN IDELFEREEL
SAAPDPGWPD CFNSGVFVYR PSIETYNQLL QFATEKGSFD GADQGLLNSF FSSWATTDMS
KHLPFIYNLS STSIYSYLPA FKAFGANTKV VHFLGSTKPW NYTYDSRTKS IKGNMDDPKI
VHPEFLNMWW ATYTANVLPL LEQHGVVKEI PTGVNMLSGL VYTLAFSCGF CREAEVTEGV
SHISISAPSP VLPTVSSEER KERWEQGQAD YMGVDSFDNI KKKLDTYLQ
//
