ID A0A093BR02_9AVES Unreviewed; 740 AA.
AC A0A093BR02;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|EMBL:KFV04593.1};
GN ORFNames=N339_02199 {ECO:0000313|EMBL:KFV04593.1};
OS Pterocles gutturalis (yellow-throated sandgrouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV04593.1, ECO:0000313|Proteomes:UP000053149};
RN [1] {ECO:0000313|EMBL:KFV04593.1, ECO:0000313|Proteomes:UP000053149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV04593.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004401};
CC Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004401}.
CC Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane
CC protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
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DR EMBL; KL229268; KFV04593.1; -; Genomic_DNA.
DR RefSeq; XP_010084969.1; XM_010086667.1.
DR AlphaFoldDB; A0A093BR02; -.
DR MEROPS; M28.012; -.
DR GeneID; 104471348; -.
DR KEGG; pguu:104471348; -.
DR CTD; 10003; -.
DR OrthoDB; 2428249at2759; -.
DR Proteomes; UP000053149; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd08022; M28_PSMA_like; 1.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR PANTHER; PTHR10404:SF38; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE 2; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053149};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022968}.
FT DOMAIN 162..248
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 347..550
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 617..737
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
SQ SEQUENCE 740 AA; 83237 MW; 69E9246FCF2C4D37 CRC64;
MARSKGTLCT WLGCPGLLGC FLLGFLAGWF TKPMGKNPNS SDVYQNEGDK LVAEMKAENI
KKFLRLFTQL PHLAGTEQNL LLAKQIQGQW KEFGLDSAEL VHYDVLLSYP NEKQPNYISI
IDDQGNEIFN TSLFEPPPQG YENVTDILPP YNAFSAQGVP EADLVYVNYG RTEDFFKLER
EMRINCTGKI VIARYGKIFR GNKVKNAILA GAQGIILYSD PADYCAPGVD PYPDGWNLPG
RGAQRGNVLN LNGAGDPLTP GYPAKEYTFR YKVNEGVGIP KIPVHPIGYH DAEVLLRAMG
GPAAPDNSWK GSLNVSYNVG PGFADSASTR KVRMHVHTNN KITRIYNVIG ILRGAVEPDR
YIILGGHRDS WVFGGIDPTT GAAVLQEVVR SFGKMKMEGW RPKRTIIFAS WDAEEFGLLG
STEWAEENAR VLQERAVAYI NTDSSIEGNY TLRVDCTPLL YKLVYNLTKE ILSPDEGYES
KSLYESWLEK DPSTDNNSYP RINKLGSGSD FEAFFQRLGI ASGRVRYTKN RKADKFSNYP
VYHTVYETFE LVEKFYDPTF KKQLTIAQLR GKLVYELADS QVIPFDCRDY GEALKGYSNQ
IYKLAKKREE QLKTYEVSFD PLFSAVVNFS KAAAEFHMRL EQVDKKDPVA VRIMNDQLMF
IERAFIDPLG LPGRKFYRHV IFAPSSHNKY AGESFPGIYD AMFDIESKAD QREAWEEVKR
QISIAAFTVQ AAAGTLKEVA
//
