ID   A0A093CA56_9AVES        Unreviewed;       973 AA.
AC   A0A093CA56;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199};
DE            EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};
DE   Flags: Fragment;
GN   ORFNames=N339_02855 {ECO:0000313|EMBL:KFV09182.1};
OS   Pterocles gutturalis (yellow-throated sandgrouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX   NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV09182.1, ECO:0000313|Proteomes:UP000053149};
RN   [1] {ECO:0000313|EMBL:KFV09182.1, ECO:0000313|Proteomes:UP000053149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV09182.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361199};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU361199};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792, ECO:0000256|RuleBase:RU361199}.
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DR   EMBL; KL236470; KFV09182.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093CA56; -.
DR   Proteomes; UP000053149; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.1360; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR   PANTHER; PTHR11607:SF28; EPIDIDYMIS-SPECIFIC ALPHA-MANNOSIDASE; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361199};
KW   Hydrolase {ECO:0000256|RuleBase:RU361199};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361199};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053149};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361199}.
FT   DOMAIN          315..398
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV09182.1"
FT   NON_TER         973
FT                   /evidence="ECO:0000313|EMBL:KFV09182.1"
SQ   SEQUENCE   973 AA;  111177 MW;  872EFF49E22FD7CA CRC64;
     FFSLQESMHA YAANVYTSVV EELMKGKQRK FIAVEQEFFR LWWDAVATDT HKQQVHQLLQ
     EGRLEFVIGG QVMHDEAVTL IDDQILQLTE GHGFLYETFG IRPQFSWHVD PFGASATTPT
     LFALAGFNAH LISRIDYDLK ADMQKNKKLQ FVWQGSPSLS ERQEIFTHVM DQYSYCTPSQ
     IPFSNRSGFY WNGIATFPDP PKDGVYPNMS LPVTETNIHA YAEAMVANIK ERAAWFQTSD
     VLWPWGCDKQ FFNASVQYSN MDLLLDYINK HSDDFGVTVQ YATVGDYFQA VYSRNLTWEI
     RDSQDFLPYS TEPFQAWTGF YTSRSTLKGI ARRASSLLYA GESFFTQYVQ KHPSSSICKC
     RALKQLQSLR WAVSEVQHHD GITGTESPKV KDMYMNNLMY GMFNVKKLMA SIIFDMNNAK
     KNGEVYSSVY NKDSGIPDVD QYVVVYNPLA WNITTFVTVS VSHLAMSVYD ELGHSVPAQV
     QSSVESPSTY DLYILVAISG LSYRKYNVKP LNGKQSAFIG RSVNYKRKDI TRADQQSRQL
     LPVVNNCYQV LFDQNTNLMH SITERETNQT IQLTQEFLEY HVNGDVMKGP ISDNYLFTPN
     ASAVPVSKAV GLEVVSGNLM TEIRQYFYSN VTAKDYIYAV YTRMYTVPEG YDGKLLCHRI
     EQEYSVGPLE LNREAVLRTS TNLNTRQLLY TDSNGYQMQK RPFKAYVNNT VARNYYPMVQ
     TAYVEDDTKR LMLLAERAHG VSSPGNGQVE VMLHRRLWNN LQWDLNYNLT LNDSSVVRPV
     IWLILGTKAL TNILCRTSGL ALEHRPVVMF GALAGDKLKL PGQLQQNSVH DSSVTVPPNL
     HLQTLSIPGW RYSSNHAEQV HSIRMGKQKQ GDADFSRILL RIRHLYEVGE DPVLSQPVMV
     NLKSLLKGLG SVMLVEERSL TGTWDINSLK RWKWKTAQYP SKRFSNSTET SENCIVTVHP
     KEIRTFFVYF QGQ
//