ID   A0A093CAE7_9AVES        Unreviewed;       488 AA.
AC   A0A093CAE7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=N-acetylglucosamine-6-sulfatase {ECO:0000313|EMBL:KFV09287.1};
DE   Flags: Fragment;
GN   ORFNames=N339_04477 {ECO:0000313|EMBL:KFV09287.1};
OS   Pterocles gutturalis (yellow-throated sandgrouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX   NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV09287.1, ECO:0000313|Proteomes:UP000053149};
RN   [1] {ECO:0000313|EMBL:KFV09287.1, ECO:0000313|Proteomes:UP000053149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV09287.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- PTM: The conversion to 3-oxoalanine (also known as C-formylglycine,
CC       FGly), of a serine or cysteine residue in prokaryotes and of a cysteine
CC       residue in eukaryotes, is critical for catalytic activity.
CC       {ECO:0000256|PIRSR:PIRSR036666-50}.
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
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DR   EMBL; KL236610; KFV09287.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093CAE7; -.
DR   Proteomes; UP000053149; Unassembled WGS sequence.
DR   GO; GO:0008449; F:N-acetylglucosamine-6-sulfatase activity; IEA:InterPro.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; IEA:InterPro.
DR   CDD; cd16147; G6S; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR012251; GlcNAc_6-SO4ase.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR43108:SF5; N-ACETYLGLUCOSAMINE-6-SULFATASE; 1.
DR   PANTHER; PTHR43108; N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   PIRSF; PIRSF036666; G6S; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
DR   PROSITE; PS00149; SULFATASE_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053149};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          9..321
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   MOD_RES         28
FT                   /note="3-oxoalanine (Cys)"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036666-50"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV09287.1"
FT   NON_TER         488
FT                   /evidence="ECO:0000313|EMBL:KFV09287.1"
SQ   SEQUENCE   488 AA;  55453 MW;  3CB5E70FE0849942 CRC64;
     QTPLKKTNAL IAQMGITFLN AYVPSALCCP SRASILTGKY PHNHHVVNNT LEGNCSSKLW
     QKIQEPYTFP ALLKTMCGYQ TFFAGKYLNE YGAEDAGGVG HVPPGWSFWY ALEKNSKYYN
     YTLSVNGKAR RHGENYSVDY LTDVLANMSL DFLEYKSNFE PFFMMISTPA PHSPWTAAPQ
     YAKSFQNVSA PRNSNFNIHG KNKHWLIRQA KTPMTNSSIQ FLDDAYRRRW QTLLSVDDLV
     EKLVKKLELN GELDNTYIFY TSDNGYHTGQ FSLPIDKRQL YEFDIKVPLL VRGPGIKPNQ
     TNKMLVANID LGPTILDIAG YDLNKTQMDG MSLLPLLRGD KNVTWRSDFL VEYQGEGYNG
     SDPTCPGLGP GVTHCFPDCV CEDSYNNTYA CVRTLSTSWD LQYCEFDDRE VFVEVYNLTA
     DPHQINNIAK TIDQEILEKM NYRLMMLQSC SGATCRTPGV FDPGYRFDPR LMFSNHGVRA
     RRFSAQSL
//