ID A0A093CJ52_TAUER Unreviewed; 1314 AA.
AC A0A093CJ52;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 22.
DE SubName: Full=Protein patched 1 {ECO:0000313|EMBL:KFV15890.1};
DE Flags: Fragment;
GN ORFNames=N340_04841 {ECO:0000313|EMBL:KFV15890.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV15890.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV15890.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV15890.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
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DR EMBL; KL465015; KFV15890.1; -; Genomic_DNA.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR InterPro; IPR004766; TM_rcpt_patched.
DR NCBIfam; TIGR00918; 2A060602; 1.
DR PANTHER; PTHR46022; PROTEIN PATCHED; 1.
DR PANTHER; PTHR46022:SF5; PROTEIN PATCHED HOMOLOG 1; 1.
DR Pfam; PF02460; Patched; 1.
DR Pfam; PF12349; Sterol-sensing; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 311..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 622..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 659..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 898..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 925..947
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 954..980
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 992..1012
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1024..1049
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 310..470
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 1058..1103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1139..1211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1064..1078
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1084..1103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1152..1168
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1169..1194
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV15890.1"
FT NON_TER 1314
FT /evidence="ECO:0000313|EMBL:KFV15890.1"
SQ SEQUENCE 1314 AA; 146536 MW; A85EB41197297284 CRC64;
YLSVGGRVSQ ELNYTRQKIG EEAMFNPQLM IQTPQEDGAN VLTTEALRQH LDSALQASRV
HVYMYNRQWK LEHLCYKSGE LITEAGYMDQ IIEYLYPCLI ITPLDCFWEG AKLQSGTAYL
LGKPPLQWIN FDPLEFLEEL KKINYQVESW EEMLNKAEVG HGYMDRPCLN PADPDCPITA
PNKNSTKPLD VALVLSGGCY GLSRKYMHWQ EELIIGGTVK NSSGKLVSAQ ALQTMFQLMT
PKQMYEHFKG YEYVSHINWN EDKAAAILEA WQRMYVEVVH QSVAQNSTQK VLSFTTTTLD
DILKSFSDVS VIRVASGYLL MLAYACLTML RWDCAKSQGA VGLAGVLLVA LSVAAGLGLC
SLIGISFNAA TTQVLPFLAL GVGVDDVFLL AHAFSETGQN KRIPFEDRTG ECLKRTGASV
ALTSISNVTA FFMAALIPIP ALRAFSLQAA VVVVFNFAMV LLIFPAILSM DLYRREDRRL
DIFCCFTSPC VTRVIQIEPQ AYAENDNTCY SPPPPYSSHS FAHETQITMQ STVQLRTEYD
PHTQVYYTTA EPRSEISVQP VTVTQDNLSC QSPESTSSTR DLLSQFSDSS MHCLEPPCTK
WTLSSFAEKH YAPFLLKPKA KIVVIFLFLG LLGLSLYGTT RVRDGLDLTD IVPRETREYD
FIAAQFKYFS FYNMYIVTQK ADYPNVQHLL YELHRSFSNV TYVLLEEDRQ LPKMWLHYFR
DWLQGLQDAF DSDWETGKIT YNNYKNGSDD AVLAYKLLVQ TGNRAKPIDI SQLTKQRLVD
ADGIINPNAF YIYLTAWVSN DPVAYAASQA NIRPHRPEWV HDKADYMPET RLRIPAAEPI
EYAQFPFYLN GLRETSDFVE AIEKVRAICS NYSSLGIASY PNGYPFLFWE QYIGLRHWLL
LSISVVLACT FLVCALFLLN PWTAGIIVVV LALMTVELFG MMGLIGIKLS AVPVVILIAS
VGIGVEFTVH VALAFLTAIG DRNHRAVLAL EHMFAPVLDG AVSTLLGVLM LAGSEFDFIV
RYFFAVLAIL TILGVLNGLV LLPVLLSFFG PYPEVSPANG RNRLPTPSPE PPPSIVRFAL
PPGHTNNGSD SSDSEYSSQT TVSGISEELH QYEATQGSGA PVHQVIVEAT ENPVFARSTV
VQPETRHQPS PRLPLNPESG TQQAWRQGRQ PKREAREGLR PPPYRPRRDA FEISTEGHSG
PSNRDRLGHR ARSHNVRSPA FGAVGAAGPA YCQPITTVTA SASVTVAVHP AVHGHSSRGG
SFPTYEGYHE ADHGPFEDPH VPFNVRCERR NSKVEVIELQ DVECEERMPG NSSQ
//
