ID A0A093DU94_9AVES Unreviewed; 649 AA.
AC A0A093DU94;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Leucine-rich repeat transmembrane protein FLRT3 {ECO:0000313|EMBL:KFV05731.1};
GN ORFNames=N339_09394 {ECO:0000313|EMBL:KFV05731.1};
OS Pterocles gutturalis (yellow-throated sandgrouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV05731.1, ECO:0000313|Proteomes:UP000053149};
RN [1] {ECO:0000313|EMBL:KFV05731.1, ECO:0000313|Proteomes:UP000053149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV05731.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC {ECO:0000256|ARBA:ARBA00004246}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004162}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004586}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL231056; KFV05731.1; -; Genomic_DNA.
DR RefSeq; XP_010086256.1; XM_010087954.1.
DR AlphaFoldDB; A0A093DU94; -.
DR GeneID; 104472329; -.
DR KEGG; pguu:104472329; -.
DR CTD; 23767; -.
DR OrthoDB; 2916435at2759; -.
DR Proteomes; UP000053149; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR GO; GO:0032584; C:growth cone membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF12; LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT3; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053149};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:KFV05731.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..649
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001885373"
FT TRANSMEM 527..552
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 406..504
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 622..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..638
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 73572 MW; B4B2E4BA6AE1EB09 CRC64;
MISVTWSIFL VWTKIGLLLD MAPYSVSAKP CPSVCRCDVG FIYCNDRDLT SIPTGIPEDA
TTLFLQNNQI NNAGIPSELK NLLRVERIYL YHNSLDEFPT NLPKYVKELH LQENNIRTIT
YDSLSQIPYL EELHLDDNSV SAVSIEDGAF RDNIYLRLLF LSRNHLSTIP WGLPKTIEEL
RLDDNRISTI SELSLQDLTN LKRLVLDGNL LNNHGLGDKV FMNLVNLTEL SLVRNSLTAA
PVNLPGTNLR KLYLQENHIN RVPPNAFSYL RQLYRLDMSN NNLSNLPQGV FDDLDNITQL
FLRNNPWHCG CKMKWVRDWL QSLPLKVNVR GLMCQAPEKV RGMAIKDLNT ELFDCKDDGM
ISTIQITTAV PNTLYPAQGH WPVSVTKQPH IKTPNLNKNY RTTASPVHKI ITIFVKSVST
ETIHISWKVA LPMTALRLSW LKMGHSPAFG SITETIVTGD RNDYLLTALE PESPYRVCMV
PMETSNIYLS DETPECIETE TAPLKMYNPT TTLNREQEKE PYKNSSLPLA AIIGGVVALV
AIALLALVCW YVHRNGSLFS RNCTYSKGRR RKDDYAEAGT KKDNSILEIR ETSFQMIPIT
NDQVSKEEFV IHTIFPPNGM NLYKNSHSES SSNRSYRDSG IPDSDHSHS
//
