ID A0A093E518_TAUER Unreviewed; 1211 AA.
AC A0A093E518;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Ras GTPase-activating protein nGAP {ECO:0000313|EMBL:KFV09556.1};
DE Flags: Fragment;
GN ORFNames=N340_00456 {ECO:0000313|EMBL:KFV09556.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV09556.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV09556.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV09556.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL456444; KFV09556.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093E518; -.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd04013; C2_SynGAP_like; 1.
DR CDD; cd05136; RasGAP_DAB2IP; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR021887; DAB2P_C.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF52; RAS GTPASE-ACTIVATING PROTEIN NGAP; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF12004; DAB2P_C; 1.
DR Pfam; PF00616; RasGAP; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661}.
FT DOMAIN 8..239
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 230..348
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 408..600
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 69..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 134..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 840..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1189..1211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1052..1125
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 95..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 868..908
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 909..927
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 962..1026
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV09556.1"
FT NON_TER 1211
FT /evidence="ECO:0000313|EMBL:KFV09556.1"
SQ SEQUENCE 1211 AA; 136662 MW; 0F7D5790159B733B CRC64;
DVKGPPTHRL SCGQSPYTET TTWERKYCIL TDSQLVLLNR EKEVPIDGIQ EPQADATKGR
CLRRTVSVPS EGQFPEYPPE GAAKLEVPAE RSPRRRSISG TSTSEKTNSM DASNTSPFKV
PGFFSKRLKG SIKRTKSQSK LDRNTSFRLP SLRNADDRSR GLPKLKESRS HESLLSPGSA
VEALDFGSEE KVFVKPLHSS ILGQDFCFEV TYSSGSKCFS CCSAAERDKW MENLRRTVQP
NKDNCRRAEN VLRLWIIEAK DLAPKKKYFC ELCLDDTLFA RTTSKTKADN IFWGEHFEFY
GLPPLHSITV HIYKDVEKKK KKDKNNYVGL VNIPMTSVTG RQFVEKWYPV STPTPNKGKT
GGPSIRIKSR YQTITILPME QYKEFAEFVT SNYTMLCSVL EPVISVRNKE EMACALVHIL
QSTGRAKDFL TDLVMSEVDR CGEHDVLIFR ENTLATKAIE EYLKLVGQKY LHDALGEFIK
ALYESDENCE VDPSKCSSSE LTDHQSNLKM CCELALCKII NSYCVFPREL KEVFASWKQQ
CLSRGKQDIS ERLISASLFL RFLCPAIMSP SLFSLMQEYP DDRTSRTLTL IAKVIQNLAN
FAKFGNKEEY MAFMNDFLEH EWGGMKRFLL EISNPDTISN MPGFEGYIDL GRELSVLHSL
LWEVVSQLDK ATVAKLGPLP RILADITKSM TNPTPIQQQL RRFTEHSSSP NVSGSLSSGL
QKIFEDPTDG DLHKLKSPTQ ENVDGYFRGK TLLLVQLFTQ SMTYSDKDER ESILPNGRSI
SLMDLQDPHA AHSDHTSTMH DVPLRLAGSQ LSVTQVANIK QLWETQSTPQ SAPQVRRPLH
PALNQQGTPQ PLSFQNPVYH LNNPTPPIPK ASVDSSLENL STASSRSRSN SEDFKLSGPS
NSSMEDFTKR STQSEDFSRR HTVPDKHVPV ALPRQNSSSQ AQIRKMDQGG LGARAKAPQS
LPHSASLRST GSVSGVSGAV VTEPVQNGSR SRQQSSSSRE SPVPKVRAIQ RQQTQQVQSP
VDSATMSPVE RTAAWVLNNG QYEEVEEDAE QNPDEVKHAE KYEQEIAKLK ERLKVSSRRL
EEYERRLLVQ EQQMQKLLME YKSRLEDSEE RLRRQQEEKD SQMKSIISRL MAVEEELKKD
HAEMQAVIDA KQKIIDAQEK RIVSLDSANT RLMSALTQVK ERYSMQVRNG ISPTNPTKLS
ITENGEFKNS S
//
