ID A0A093EEK6_TAUER Unreviewed; 661 AA.
AC A0A093EEK6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 35.
DE SubName: Full=Calpain-14 {ECO:0000313|EMBL:KFV12931.1};
DE Flags: Fragment;
GN ORFNames=N340_08393 {ECO:0000313|EMBL:KFV12931.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV12931.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV12931.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV12931.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C2 family.
CC {ECO:0000256|ARBA:ARBA00007623}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL460975; KFV12931.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093EEK6; -.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00214; Calpain_III; 1.
DR CDD; cd00044; CysPc; 1.
DR CDD; cd16195; EFh_PEF_CAPN13_14; 1.
DR Gene3D; 2.60.120.380; -; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR033883; C2_III.
DR InterPro; IPR022684; Calpain_cysteine_protease.
DR InterPro; IPR022682; Calpain_domain_III.
DR InterPro; IPR022683; Calpain_III.
DR InterPro; IPR036213; Calpain_III_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR001300; Peptidase_C2_calpain_cat.
DR PANTHER; PTHR10183; CALPAIN; 1.
DR PANTHER; PTHR10183:SF302; CALPAIN-14; 1.
DR Pfam; PF01067; Calpain_III; 1.
DR Pfam; PF00648; Peptidase_C2; 1.
DR PRINTS; PR00704; CALPAIN.
DR SMART; SM00720; calpain_III; 1.
DR SMART; SM00230; CysPc; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF49758; Calpain large subunit, middle domain (domain III); 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50203; CALPAIN_CAT; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00239}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU00239}; Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807, ECO:0000256|PROSITE-
KW ProRule:PRU00239}.
FT DOMAIN 16..322
FT /note="Calpain catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50203"
FT DOMAIN 533..568
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 570..598
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT ACT_SITE 74
FT /evidence="ECO:0000256|PIRSR:PIRSR622684-1,
FT ECO:0000256|PROSITE-ProRule:PRU00239"
FT ACT_SITE 240
FT /evidence="ECO:0000256|PIRSR:PIRSR622684-1,
FT ECO:0000256|PROSITE-ProRule:PRU00239"
FT ACT_SITE 264
FT /evidence="ECO:0000256|PIRSR:PIRSR622684-1,
FT ECO:0000256|PROSITE-ProRule:PRU00239"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV12931.1"
FT NON_TER 661
FT /evidence="ECO:0000313|EMBL:KFV12931.1"
SQ SEQUENCE 661 AA; 76324 MW; 3C6D778BD977BCBE CRC64;
QNYQALLETC LKNKCLFIDD SFPAHISSIG TGALLKKLPR NLQWKRPHDL HRSPVFYAGN
RKQLDLCQGL VENCWFLAAL EALTFHQDIL AAVVPQNQSF ERKYAGIFHF RFWHFGEWVD
VVVDDRLAVN EAGELVFVSS VYKNVFWGAL LEKAYAKLYG SYEDLQIGQV SEALVDFTGG
VNTRINLAAA PPDLWDILTR ATYSRSLMGC QTHLGVYFPS VSLPCIQTTK VLKNGLVAGH
AYTVTGIRKV TCQYGPENLV RLRNPWGKIE WKGDWSDSSY KWELLSPKEK ILLRKKKEDG
EFWMSLRDFK IHFVDLTICK LTPDLMSQED GKKWMYSLKS GRWVKGSTAG GSLGFCNGTF
WMNPQYWLKV LPVEDSKKNL GSCNVIISLM QKHSSKHRNR APHLFIGFSL YKYQESNRKL
LPAFFTHHQP VNKHQVFLDE REVTQDFHLE PGVYVIVPST LKPQQESEFI LRVFSRKHVL
RDPANYCKRW KRFTFQKRWL HLFSSNPEIN AVQLQRILNN VSWRNFPSFS LSFSLDACQG
ILALLDLNAS GTLSIQEFRV LWKRLLFYLE VFQKRDTSRS GKLDLMELHA AVQETGISLS
NEVCNLMAIR YGDPDLKISF ESFVCFMLRV EIMGEAFRNL TQDGKGIYLQ ESEWMMMTLY
S
//
