ID A0A093EM38_TAUER Unreviewed; 948 AA.
AC A0A093EM38;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Ras and Rab interactor 3 {ECO:0000313|EMBL:KFV15586.1};
DE Flags: Fragment;
GN ORFNames=N340_02182 {ECO:0000313|EMBL:KFV15586.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV15586.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV15586.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV15586.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RIN (Ras interaction/interference) family.
CC {ECO:0000256|ARBA:ARBA00006919}.
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DR EMBL; KL464694; KFV15586.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093EM38; -.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd16130; RA_Rin3; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR045046; Vps9-like.
DR InterPro; IPR037191; VPS9_dom_sf.
DR PANTHER; PTHR23101; RAB GDP/GTP EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23101:SF58; RAS AND RAB INTERACTOR 3; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF02204; VPS9; 1.
DR SMART; SM00314; RA; 1.
DR SMART; SM00167; VPS9; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF109993; VPS9 domain; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS51205; VPS9; 1.
PE 3: Inferred from homology;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 36..130
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 672..815
FT /note="VPS9"
FT /evidence="ECO:0000259|PROSITE:PS51205"
FT DOMAIN 849..934
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 245..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..413
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..496
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV15586.1"
FT NON_TER 948
FT /evidence="ECO:0000313|EMBL:KFV15586.1"
SQ SEQUENCE 948 AA; 105829 MW; D4CA9B92058A0594 CRC64;
EEGKETYLCQ DTALQNCLPL PGISILDKLI KTCPVWLQLN MNQERAGAIL GKETAGIFLV
RKEGNMNNMV LAVRLPVQNE DPAVLEYNIK EEKSILYLEG SVLVFEDVFK LVAFYCVSRD
LLPFTLKLPQ AILEASSFQD LEIISSLGID FWDSSLNHRR REELSHPAKD TAFITAQADS
LRSTQCFASS TNHCSCEIEL SIGNDRLWFV NPIFIEECSN PFPPDVPPPK SYAVSTNLSP
ATMITERKSP RRPPPPPPSH APVQKSSLKL LQGPMTACEE NELFLQPLGK SIKEMKIEGG
DNKEEEGKQS CSVNEPSAVS PKKGSQPSVP PRRRLCERTL EESCAGKPGS CETLKGERTE
EKQDTSTESR DKRSLCKKAA EMPGEVPERA VSQFQETKPE PVEKKEDMPE IQSNAIEKGK
TPPIPPPRRK RLSQVPRISS SCQSMQRTVA EMATATEQAL GKSSSATVAG DATCTRTKTE
PGHSCKSASS AELKGSHSSL EGPGGSVVAQ ASASEPDSYS TSSTEDDLEM LSSSSGKKTR
SMILNKAKNR LSFVSLSNVF TVFLSSDRKL QKKIVELAQD KDSYFGNLVR DYRVYSLEMM
AKQSSSTEML QEIRMMMTQL KSYLVQSTEL KSLIDPTSYT EEQLEVIAET ALYKCVLKPL
KEAIDSYLKE IHNKDGSLQQ LKENQLVIQN TTTTDLGITT SVPETVVLEK ILHKFTTMHK
AYSPEKKIAI LLKSCKLIYD SMAQGNPGKP YGADDFLPVL MYVLARSNLT EVLLNVEYMM
ELMDPALQLG EGSYYLTTTY GALEHIKNYD KITVTRQLSV EVQDSIHRWE RRRTLNKARA
SRSSVQDFIS ISFLEIGAQS RTLASRNDTT AEQLSQQCAE KFEVSHPKDY GLFVYVDDQW
LQLDKDALPH HIKSSLLKSE TKKDFHFIYK PIDHKTPPVP IVKESDFS
//
