ID A0A093EPJ6_TYTAL Unreviewed; 688 AA.
AC A0A093EPJ6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Leucine-rich repeat and WD repeat-containing protein 1 {ECO:0000256|ARBA:ARBA00015536};
DE AltName: Full=Origin recognition complex-associated protein {ECO:0000256|ARBA:ARBA00033046};
GN ORFNames=N341_05522 {ECO:0000313|EMBL:KFV41815.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV41815.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV41815.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV41815.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the LRWD1 family.
CC {ECO:0000256|ARBA:ARBA00007545}.
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DR EMBL; KK367365; KFV41815.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093EPJ6; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR24370:SF10; LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24370; OPTICIN; 1.
DR Pfam; PF12799; LRR_4; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Telomere {ECO:0000256|ARBA:ARBA00022895};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 411..445
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 215..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 77802 MW; 60B1227386065A99 CRC64;
MSKITTELLL ERAVPRSTRL RKIETLNLSK LQLKTGDLDP RLFSRLRHLQ KLDLSDNLLD
KFPNSLTLPD LRVLNCNNNK LEDVTALKQF PLLEELTYEN NVYLTLNDDY KVMFLLQNLR
LLNGKDITKL ANHVRRVNSR KLTSKVTAHW KKFFRDQLPE KYTAEQVKAI KKKFLKSVQT
NVVYGPSSLS EFTRWRVKMI AEEFLAYSLG LELNTDPEPE EARDENEEES TESPREAAEV
VDQVVYIYDL LVTVVPSKRK RSNSKAGSGN KRAKSQAKTK EAAAEDVSAE PLHFLQCHSK
GNSREDFKTQ LWSCVFEPLL DCGARKDPIV SSSRTVATCG GESVCLIDCE TGTVLKKYKV
TTEEFFSVAW TTLTMVISDS RKKSHNILAA AGRRGIVKLI HVAADFCYGE IKAHKKPIAT
VCFSPTRETH LFTASYDKRI ALWDIGIPDC DYNFKASQLL VLEALSIPLR IALVPTCPDQ
YLLAGCEGGC FAWNIKLDKE QKSRQEPKAG AMHLPFEVLF QFPDEDGGMS TSHRVDGVAF
LNDDIVVSKS SKLGCIYLWS WSRSFDTKGK GCQRTVAAFI LAELEWSTTD LSYLTLSTCP
AKDYVFCGDE KGSVWMYNLS KYITAWSSAK GKRSDKRIPP SQILQWPELR TNSEQLTEVL
INNVVSDPTF TYLVVLTSVN ITAIWKKS
//
