ID A0A093EPU4_GAVST Unreviewed; 789 AA.
AC A0A093EPU4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 03-MAY-2023, entry version 39.
DE SubName: Full=Guanine nucleotide exchange factor DBS {ECO:0000313|EMBL:KFV47337.1};
DE Flags: Fragment;
GN ORFNames=N328_12982 {ECO:0000313|EMBL:KFV47337.1};
OS Gavia stellata (Red-throated diver) (Colymbus stellatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gaviiformes; Gaviidae; Gavia.
OX NCBI_TaxID=37040 {ECO:0000313|EMBL:KFV47337.1, ECO:0000313|Proteomes:UP000054313};
RN [1] {ECO:0000313|EMBL:KFV47337.1, ECO:0000313|Proteomes:UP000054313}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N328 {ECO:0000313|EMBL:KFV47337.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK613363; KFV47337.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093EPU4; -.
DR Proteomes; UP000054313; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd01227; PH_Dbs; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd00176; SPEC; 1.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR035534; DBS_PH.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR PANTHER; PTHR22826:SF115; GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS; 1.
DR PANTHER; PTHR22826; RHO GUANINE EXCHANGE FACTOR-RELATED; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00150; SPEC; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054313}.
FT DOMAIN 1..70
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 468..648
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 660..782
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 419..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV47337.1"
FT NON_TER 789
FT /evidence="ECO:0000313|EMBL:KFV47337.1"
SQ SEQUENCE 789 AA; 91080 MW; FD36655EEBA9D846 CRC64;
SFPGNLQLVL VLRPTGFFHR ALSDIAFKFN KDEFKMKVPI IMLGSVSELQ GYIDKTQLTE
DLGGTLDYCH NRWLSRRTAI EGFAQKVKQT AQILQSFGTE LAETELPNDV QSTSSLLATH
TEKKDKMKED IRLAVEQGDD ILGSITKPVT ENPEYKLNQD QLDNQATVER LLAQLHETET
AFDEFWIKHQ QKLEQCLHLR NFEQNFREVK AALNIVSERL SAFTDVGKSC SHVEHILKDL
ANFEEKSCET IVKARMLASE GDAFIQSNHY AVDSVIPKCS ELHHLCDAFT TETERRRNLL
NKSLELHGLL EKSMKWCDEG IYLLASQPVD KCQSQDGAES ALQEIEKFLD TGTGNKIKEL
NKIYREYAHI LSEDLKEHVQ KVFQKQESME EMFQKRQVSL KKLAAKQTRP VQPVAPRPEA
FVKSPCTSPE TMRGGQQEHM TSRDNSWRKG LVQGGIECRT SHFFQQAVIR HVINELIETE
RAYVEELLCV LEGYAAEMDN PLMAHLIPPE LQNKKDILFG NMEEIYHFHN RIFLRELENY
VEYPELVGRC FLDQMEDFQI YEKYCQNKPR SESLWRQFSD SVFFQECQRK LDHKLSLDSY
LLKPVQRITK YQLLLKEMLK YSKNCEGAED LQEALTSILG ILKAVNDSMH QIAITGYDGN
LNELGKLLMQ GSFNVWTDHK KGHSKVKDLA RFKPMQRHLF LHEKAVLFCK KREENGEGYE
KAPSYSYKHS LNMAAVGITE NVKGDAKKFE IWYNAREEVY IIQAPTPEVK ATWVNEIRKV
LTSQLQACR
//
