ID A0A093ERB4_TYTAL Unreviewed; 935 AA.
AC A0A093ERB4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 28-JUN-2023, entry version 36.
DE SubName: Full=Papilin {ECO:0000313|EMBL:KFV42933.1};
DE Flags: Fragment;
GN ORFNames=N341_09522 {ECO:0000313|EMBL:KFV42933.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV42933.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV42933.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV42933.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK369771; KFV42933.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093ERB4; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR CDD; cd22635; Kunitz_papilin; 1.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 4.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF179; PAPILIN; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 3.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 1.
DR SMART; SM00209; TSP1; 4.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 4.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS50092; TSP1; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 738..788
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 905..935
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 544..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..815
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 18..54
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 22..59
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 33..44
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV42933.1"
FT NON_TER 935
FT /evidence="ECO:0000313|EMBL:KFV42933.1"
SQ SEQUENCE 935 AA; 101963 MW; F3C5B3B5779EF5F5 CRC64;
RMKRQLDVWG SWGEWGKCSR SCGGGVSFRQ RRCYSQRTEG ASSCVGPTRS YRSCNIQSCP
EGSQDFRAEQ CAEFDGTEFQ GKKYKWLPYY GAPNKCELNC IPKGENFYYR HKEAVVDGTT
CEPGKRDICV EGVCQAVGCD NMLESAKKED KCLQCGGDGS TCYGVKGTFD VPSLPKGYNQ
IFIIPVGATS IQIKEVMPSR NFLAIKNVRG EYYLNGHWTI DFSRALKVAS TIMHYDRGSE
GDLAPELLHA QGPTTEPLVI ELISQEPNPG VQYEYYLPVQ GQASGYSWSY GSWRYSLASP
LGFQSRLVFC TIDNEIYPDY MCRSKPQPDN NRTCGHQTCP QTKRWKTGEW GSCSATCGGG
TQTRSVYCVA FDGQSSQGVV DNAECMAFAQ QPRSSQPCNV RQCATWSTGP WSECSASCGE
GVQTRTVTCR TQQGSQAQDF SCLMEPKPSA TQPCLKENCI QEIGWHVGDW GLCSKSCSSG
IRTRQVICAD GDSKFYSPET CKAIQPQKPA TLGSCNMQPC YLPQQVPSMQ DTMGYDVTRQ
SLLTRYNPNG PATDSGDERM LSGSSTIQST SGNHYIPSTK DRGINLLPVR WESQSRSSGS
HQLSFSQDPP GGAGSQDCQR SPHGCCPDGH TPASGPLGRG CSFSSCHRNR YGCCPDGVSA
AQGPNNMGCP QYYRDVQVSR NQPTAATPTA SQALSQQYPS GECRSSVYGC CFDNVASASG
PRGEGCLNRP NYPYPVICLL PSAHGPCANW TTRWYFVTVV GKCNRFWYGG CHGNKNSFAS
EEECMRVCHN SEGVSPLEHQ PSSGTGALQH QHTGSRSHTG DARAVPGPSE RRRSGGGEQW
HKAFGADVSV TEGFGHQASA DSFPAWALHR GARGEEGCRG ANRITFSFRA ILEEAKPSLV
TAVVGQNVQL VCKTGVSPSS RVEWVKDGRP VSSDR
//
