ID A0A093ERS4_TYTAL Unreviewed; 1804 AA.
AC A0A093ERS4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE Flags: Fragment;
GN ORFNames=N341_03308 {ECO:0000313|EMBL:KFV43128.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV43128.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV43128.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV43128.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KK370088; KFV43128.1; -; Genomic_DNA.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18666; CD1_tandem_CHD1-2_like; 1.
DR CDD; cd18661; CD2_tandem_CHD1-2_like; 1.
DR CDD; cd18054; DEXHc_CHD2; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 6.10.140.1440; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR040793; CDH1_2_SANT_HL1.
DR InterPro; IPR025260; CHD1-like_C.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR023779; Chromodomain_CS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623:SF19; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 2; 1.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR Pfam; PF18375; CDH1_2_SANT_HL1; 1.
DR Pfam; PF13907; CHD1-like_C; 1.
DR Pfam; PF00385; Chromo; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01176; DUF4208; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00598; CHROMO_1; 2.
DR PROSITE; PS50013; CHROMO_2; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:KFV43128.1};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFV43128.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 236..328
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 353..430
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 470..640
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 769..920
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1004..1101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1304..1437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1530..1622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1651..1804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..175
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..226
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1014..1044
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1054..1101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1325..1410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1531..1552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1561..1586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1598..1620
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1662..1676
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1677..1726
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1752..1766
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1775..1790
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV43128.1"
FT NON_TER 1804
FT /evidence="ECO:0000313|EMBL:KFV43128.1"
SQ SEQUENCE 1804 AA; 209115 MW; DA90FB455F9D268D CRC64;
SHSASEEASG SDSASQSESE QGSDSNSSSE SSESQSESES ESTGSKSQQT PPETKEKPAS
KKERIADVKK MWEEYPDVYG VRRSNRSRQE PSRFNIKDEA SSESENESPK RRGQKQMKKA
EVSGEEEDED GGEQGTSGES EPEPKKVKAR RPAQRRTVAK TTVKKPHKPQ RGKKRKKQVS
SEDDDDDEDD ETPKRQTRRR AAKNVSYKED DDFETDSDDL IEMTGEGADE QQDNSETIEK
VLDIRLGKKG ATGASTTVYA TEANGNPSAD FDPEKDEGEV QYLIKWKGWS YIHSTWESEE
SLQQQKVKGL KKLENFKKKE EEIKQWLGKV SPEDVEYFNC QQELASELNK QYQIVERVIA
VKTSKSATGH SDFPANSRKT SSNDPEYLCK WMGLPYAECS WEDEALISKK FQHCIDSFNN
RNNSKTIPTR DCKVLKQRPR FVALKKQPSY IGGENLELRD YQLEGLNWLA HSWCKNNSVI
LADEMGLGKT IQTISFLSYL FHQHQLYGPF LVVVPLSTLT SWQREFEVWA PEINVVVYIG
DLMSRNMIRE YEWIHAQSKR LKFNALITTY EILLKDKAVL GSINWAFLGV DEAHRLKNDD
SLLYKTLIDF KSNHRLLITG TPLQNSLKEL WSLLHFIMPE KFEFWEDFEE DHGKGRENGY
QSLHKVLEPF LLRRVKKDVE KSLPAKVEQI LRVEMSALQK QYYKWILTRN YKALSKGTRG
STSGFLNIVM ELKKCCNHCY LIKPPEENER ENGLETLQSL IRSSGKLILL DKLLTRLRER
GNRVLIFSQM VRMLDILAEY LTIKHYPFQR LDGSIKGEIR KQALDHFNAD GSEDFCFLLS
TRAGGLGINL ASADTVVIFD SDWNPQNDLQ AQARAHRIGQ KKQVNIYRLV TKGTVEEEII
ERAKKKMVLD HLVIQRMDTT GRTVLDNNSG RSNSNPFNKE ELTAILKFGA EDLFKELEGE
ESEPQEMDID EILRLAETRE NEVSTSATDE LLSQFKVANF ATMEEEETEL DERSQKDWDD
IIPEEQRKKV EEEERQKELE EIYMLPRIRS STKKAQTNDS ESDAETKRRL QRSSGSESET
DDTDDEKRPK RRGRPRSVRK DTVEGFTDAE IRRFIKAYKK FGLPLERLEC IARDAELVDK
SVADLKRLGE LIHNSCVSAM QEYEEQLKEN PGEGKGPGKR RGPTIKISGV QVNVKSIIQH
EEEFEMLHKS IPTDPEERKK YRLTCRVKAA HFDVDWGVEE DSRLLVGIYE HGYGNWELIK
TDPELKLSDK ILPVETDKKP QGKQLQTRVD YLLKLLKKDL DKKENMKDGE EGKLKKRKPR
VKKENKAPKV KDEHGNELSS PRHSDNQSEE GEVKEDGLEK SPVKKKQKKK ENKENKEKQT
TTKKEKESDK EKKKTKDKKE KPKGGESKSG SKGKRSQGPV HITAGSEPIP IGEDEDDDLD
QETFSVCKER MRPVKKALKQ LDKPDKGLTV QEQLEHTRNC LLKIGDRISE CLKAYTDQDH
IKLWRRNLWI FVSKFTEFDA RKLHKLYKMA HKKRSQEEEE QKKKEDMSSM KKPFRPEPSG
SSRDSVMSQS HVPHNPHSQK IHLPPSHAQQ QMHGHPRDNY GHPNKRHFSN TDRGEWQRDR
KFNYGGNSNQ MWGGERHHQY EQHWYKDHHY GDRRSRGEPH RSSGNYRPNN LSRKRPYEQY
NSDRDHRGHR DYYDRHHHDS KRRRSDEFRP QNYHQQDFRR MSDHRPPMGY HGQGPSDHYR
SFHTDKLGDY KQPLPPPHPA VSDPRSPPSQ KSPHDSKSPL DHRSPLDRSL EQKNNPDYNW
NMRK
//
