ID A0A093ES21_TYTAL Unreviewed; 3251 AA.
AC A0A093ES21;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Laminin subunit alpha-3 {ECO:0000313|EMBL:KFV43378.1};
DE Flags: Fragment;
GN ORFNames=N341_07001 {ECO:0000313|EMBL:KFV43378.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV43378.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV43378.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV43378.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Secreted, extracellular space, extracellular matrix, basement membrane
CC {ECO:0000256|ARBA:ARBA00004302}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; KK370645; KFV43378.1; -; Genomic_DNA.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 14.
DR CDD; cd00110; LamG; 5.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 10.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009254; Laminin_aI.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR000034; Laminin_IV.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF435; LAMININ SUBUNIT GAMMA-1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00052; Laminin_B; 1.
DR Pfam; PF00053; Laminin_EGF; 14.
DR Pfam; PF00054; Laminin_G_1; 1.
DR Pfam; PF02210; Laminin_G_2; 4.
DR Pfam; PF06008; Laminin_I; 1.
DR Pfam; PF06009; Laminin_II; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 8.
DR SMART; SM00180; EGF_Lam; 14.
DR SMART; SM00281; LamB; 1.
DR SMART; SM00282; LamG; 5.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 12.
DR PROSITE; PS01248; EGF_LAM_1; 3.
DR PROSITE; PS50027; EGF_LAM_2; 9.
DR PROSITE; PS50025; LAM_G_DOMAIN; 5.
DR PROSITE; PS51115; LAMININ_IVA; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Basement membrane {ECO:0000256|ARBA:ARBA00022869};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..202
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 332..375
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 393..437
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 438..490
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 533..585
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1179..1224
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1269..1317
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1318..1368
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1389..1568
FT /note="Laminin IV type A"
FT /evidence="ECO:0000259|PROSITE:PS51115"
FT DOMAIN 1602..1648
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1649..1701
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 2304..2507
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2514..2676
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2683..2840
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2911..3077
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 3079..3249
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT COILED 1936..1973
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2016..2084
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2131..2193
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2253..2297
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 351..360
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 393..405
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 413..422
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 438..450
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 440..457
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 459..468
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 556..565
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1179..1191
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1181..1198
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1200..1209
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1293..1302
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1318..1330
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1320..1337
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1339..1348
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1621..1630
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1649..1661
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1672..1681
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV43378.1"
FT NON_TER 3251
FT /evidence="ECO:0000313|EMBL:KFV43378.1"
SQ SEQUENCE 3251 AA; 360238 MW; 96AACC6980247FD7 CRC64;
FQGQFCDYCN AADPSKAHPV TNAVDGTERW WQSPPLSMGL KYNEVNVTLD LGQLFHVAYI
LIKFANSPRP DLWILERSVD FGRTYTPWQY FAHSKADCLE RFGKEANLPV RRDSDVLCTT
EYSRILPLEN GEIVVSLVNG RPGAKNFTYA PSLREFTKAT NIRLHFLRTN TLLGHLISKA
QRDPTVTRRY YYSIKDISIG GRCVCHGHAE VCNAKSAENQ YQFQCECQHN TCGETCDHCC
PGYNQKQWQP ATAGSTNICE PCNCHEHATD CYYDADVDQR RESLNIHGHY EGGGVCINCQ
HNTAGINCEK CAKGYYRPYG VPARAPDSCI PCSCNLEHAG GCEEGSGRCF CKENFQGENC
ERCADGFYGY PFCVRIPVYP FTSPNPSDAM AVCKCNLVGT QPEVCDFLGR CLCRSGVAGL
QCDGCQPGRH SFPACQACQC SAGGSQHSTC EPALGQCACQ PGVTGRRCDR CLSADDTFPY
CKGVNNECDP SGSIGSHSGY CQCLQHVEGP TCSKCKPLYW NLAKGNPEGC TACHCDVSGT
LSGVGECQQE NGHCYCKSNV CGDSCDTCEA GYYALKNKNY FGCQGCRCDV GGSLSAACAE
PSGGCHCRAH IVGTACQEPE KNYFFPDLHH MKFEIEDGTT VKGREIRFGY DPQEFPGFSW
RGYAQMSSIQ NEVRITLNVE KSNLYLFRII LRYINPGGET LSGRISACQS RPEAGTAQSK
EFVFPPSKEP AFVTIPGKNS TDPFSLVPGT WTVSIMAEEV LLDYMVLLPS DYYEASILQI
QVTEPCTYSG HASTEHCLLY QHLPLARFSC VLGSDAAYFR HGGEYRRILV RQPTPDQPVM
THISGREVNL QMTISVPQVG RYVLVFEYAN EEDQLYTAEV IIHSPGPVTE GRVRIYSCKY
SFLCRSIVVD DRNRVAAYDL LADTKIHIKA SSINFLLHKV CIISVEEFSP GYVDPKVQCI
AAYRSTRDGS ATCIPSVYDT PPAALVLDAL KDGKISEVQR NILYDPLSAP LPSDSVNGVT
LTPLQSQITL SGRVPHLGRY VFVVHFYQPE HPVFPVQVRV DAGRVWSGSF NASFCPHTAG
CRDQVVAERQ IELDISEPEV SVTVMIPDGR MLVLENVLVV PADSYSYKIL DKKTVDKSFD
FISQCGGNSF YIDPEGSSAF CKDSVRSLVA FYNNGALPCN CHSTGATNPT CSPLGGQCIC
RPNVIGRQCS RCQTGYYGFP FCKLCNCGQR LCDDVTGKCI CPPRTVKPKC EVCEKHYFSY
HPLSGCESCN CSERGVVNVA SPECEKNSGQ CKCKPGIKGR QCDQCAPGTY GFPNCVLCNC
NRDGTEPDVC DPQTGICLCK ENVEGAECDT CRPGSFYLDP SNPRGCTSCF CFGATSNCRS
TNHRRTKFVD MRNWHLEAVD ENIDIPVTFN PVSNSVVADV QELPASVHSL YWKAPPSYLG
EKLSSYGGFL SYQVKSFGLP SEGMVLLDKR PDVQLTSQQM KVVYMDPNNP LPDRQYYGRV
QLVEGNFRHA SSNNLVSREE LMIILSRLDG LHIRGLYFTE TQRLTLGEVG LEEATSSGSG
SIAYSVETCS CPPEYAGDSC QECGLGFYRE NKGLFTGRCV PCNCNGNSNK CQDGTGKCIN
CQYNTAGEKC ERCKDGYFGD ATQGSCRVCP CPYTNRFATG CVANGEEIQC LCKEGYTGIR
CERCAPGYFG NPQKYGSYCQ KCNCNNNGQL AGCDHLTGEC FNNEPKDVDP NEDCDSCDSC
VITLLKDLST IGDELQLIKS QLQNVRASTH TLEQMRHLET RIKDLKVLLN NYHSVVHNQG
SKADELETKF IKLNHDVNAL QEKAEMNYKT AERLFNNFGQ THQKGKDLVS QIQIVVNNIQ
VLLEQIAGTN AEGNNLPLGD AAKELAEAQR MMMEMRNRNF GQLQAEAEKE GTEAQLLLAH
IKNELQKYHQ ENHGLIKIVR DSLNEYESKI IDLREALNEA TGQIKQAENL NRDNGDLLED
IKKRIEETNV QQNGVLDILS SARSSLMQAN SVLGLLQKSK EEYESLAAQL DGARKDMNEK
LTNNSLSASK EPLVVRAEEH AKSLQDLAKQ LEEIKNSARK DELVGCAVEA STAYDNIINA
IKAAEEAANK AGNAADSALS TVKREDLSGK AANLKTESST LLNQAQETQK TLQAIGPTLE
DINQRLGVAD GKKNTLQIDL VTLQNNLNGI NRDDIDSIIT SAKNMVKSAK DVTTNVLDEL
LPIQVDVEKM KSTYGSTQSA GFSKALMEAN NSVKKLTNKL PDLFSKIENI NQQLMPITNI
SENVNRIREL IQQARDAANK VAIPMRFNGS SGVEVRPPSN LEDLKGYTSL SFFLQRPQTR
LDIPQRASNK FVLYLGNKDA SKDYIGMAVK DGHLTCVYNL GDGDVEIDVQ PFVTESKTEE
AVMDQVKFER IYQYVKLNYI KEATSASPEY EHPLTASSGG SDTLLNLDPS TVVFYVGGYP
PEFRPPRKLD YPHYEGCIEL DNLNEHIISL YNFKRTFNLN TTEVQPCRRY KEETDQSYFE
GTGYASVTLK EPNTHSRVRY EQTIETTADE GIVFFAANGD QFISVLIKDG HTVFRYKVGS
EPPKEIETNA TVNDGTYKQI HLVLARSKNT VHVSPDIKAN IKVFLFTKYY LGGIPPSLRE
RFNISTPPFR GCMKNVKNPN TASVIFDETV GVSKKCSDDW KLVRSAAFSR KGTLSLSAAG
FPFPKDFQVG FGFQTTTSTG TLLNYNLWPN ILTIFLRPGS VTAKMGEKEI ELKKKYEDGS
MHYVTVIKTD NIVHLLVDDE STLASVEPLR GRALIEPIKF GGDNFKGCIS NIFIKRAGQL
PEVQNLVNYT AKTGVSLGAC RKYENVEPML LKEFKNPLRF KMLKVCLLLL KCFHSVLQIQ
NEKYLDFLKA ANVQNQEDHT LSAELNVSSE AYLFGNIPNS FISYMFSPLS STDRLHFSVD
VRTRSSRGLI VFMEERSEDS YMALHISKGR FVLSLGSGGK RIKIKTSVKY NDGQWHTVVF
STDGRNVRLV VDGLRAQHGR LATNSAISIK PPIYVGGLPS LKRQNIPMDS FKGCLRNFKM
NAKVMNAAQE KNGVLPCLDV PMDTGIYFFN EGGYITFGKM CRDYDIWNYI LSILLHTGSK
QDNYLTIYIE GGKVVVAGNS GAGEFQTSVT PEQPLSDGQW HTIAVSQKEN TVQLEVGTQS
NYTTGLPLSP PRRVYQPLYF GKIPANLDTL WLPVKDPFVG CLRNVNINDK HLSSRRISEV
HGAVSLHGCP A
//
