ID A0A093ETA3_TAUER Unreviewed; 229 AA.
AC A0A093ETA3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=R-spondin-1 {ECO:0000313|EMBL:KFV17751.1};
DE Flags: Fragment;
GN ORFNames=N340_06543 {ECO:0000313|EMBL:KFV17751.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV17751.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV17751.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV17751.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the R-spondin family.
CC {ECO:0000256|ARBA:ARBA00007308}.
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DR EMBL; KL467945; KFV17751.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093ETA3; -.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00064; FU; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR043601; Rspo_Fu-CRD_dom.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR044004; TSP1_spondin_dom.
DR PANTHER; PTHR46987; NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46987:SF5; R-SPONDIN-1; 1.
DR Pfam; PF15913; Furin-like_2; 1.
DR Pfam; PF19028; TSP1_spondin; 1.
DR SMART; SM00261; FU; 2.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS50092; TSP1; 1.
PE 3: Inferred from homology;
KW Heparin-binding {ECO:0000256|ARBA:ARBA00022674};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 11..111
FT /note="R-spondin Fu-CRD"
FT /evidence="ECO:0000259|Pfam:PF15913"
FT DOMAIN 117..172
FT /note="Spondin-like TSP1"
FT /evidence="ECO:0000259|Pfam:PF19028"
FT REGION 174..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV17751.1"
FT NON_TER 229
FT /evidence="ECO:0000313|EMBL:KFV17751.1"
SQ SEQUENCE 229 AA; 25392 MW; FEE5C1692122BD42 CRC64;
VSTELSQGCA RGCDLCSEFN GCLRCSPKLF ILLERNDIRQ IGICLPSCPL GYFGLRNTDM
NKCIKCKIEN CESCFSRNFC TKCKEGLYLH KGRCYVTCPE GYSAANGTME CSGPAQCEMS
EWGPWGPCSK KRKLCGFKKG NEERTRRILQ APSGDMSLCP ATTEVRRCTV QKNQCPEGKR
KKKEEQGKQD NANGNRNRKD TKDAKSGTKK RKSKQRGAAV PATSTSPAQ
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