ID A0A093F0G6_TYTAL Unreviewed; 633 AA.
AC A0A093F0G6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Extracellular sulfatase Sulf-2 {ECO:0000313|EMBL:KFV47706.1};
DE Flags: Fragment;
GN ORFNames=N341_11152 {ECO:0000313|EMBL:KFV47706.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV47706.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV47706.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV47706.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SUBCELLULAR LOCATION: Cell surface {ECO:0000256|ARBA:ARBA00004241}.
CC Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00004240}. Golgi apparatus,
CC Golgi stack {ECO:0000256|ARBA:ARBA00004348}.
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR EMBL; KK379715; KFV47706.1; -; Genomic_DNA.
DR RefSeq; XP_009962529.1; XM_009964227.1.
DR AlphaFoldDB; A0A093F0G6; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR024609; Extracellular_sulfatase_C.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR43108:SF4; EXTRACELLULAR SULFATASE SULF-2; 1.
DR PANTHER; PTHR43108; N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER; 1.
DR Pfam; PF12548; DUF3740; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190}.
FT DOMAIN 35..128
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT DOMAIN 286..427
FT /note="Extracellular sulfatase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12548"
FT COILED 391..418
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV47706.1"
FT NON_TER 633
FT /evidence="ECO:0000313|EMBL:KFV47706.1"
SQ SEQUENCE 633 AA; 74007 MW; 59FEA6D96B8BEDFF CRC64;
TPSYNYAPNP DKHWIMRYTG PMKPIHMEFT NMLQRKRLQT LMSVDESMEM IYNMLVETGE
LDNTYIIYTA DHGYHIGQFG LVKGKSMPYE FDIRVPFYVR GPNVEAGSLN PHIVLNIDLA
PTILDIAGLD IPSDMDGKSI LKLLDSERPV NRFHLKKKMK VWRDSFLVER GKLLHKRENE
KVDAQEENFL PKYQRVKDLC QRAEYQTACE QLGQKWQCVE DASGKLKLHK CKGMSNLAAA
GNSKGTSNIL PKYYNRNSED CNCEENEYKL SHVGRRKKLF SKKKYKPSYV RNRSIRSVSV
ELDGAVYNLG LEDGYQPVLP RNITKRHKMQ RAILHEEEDK DMGEYSGTGG LAEYAAPNLI
KVTHRCYILE NDTVQCDTDL YRSLQAWKDH KLHIDHEIET LQNKIKNLRE VRGHLKKKRP
EECDCNKISY HSKHKSKLRH KGSGLHPFKK ALQEKDRLWL LREQRRKKKL RKLLKRIKNN
DTCSMPGLTC FTHDNQHWQT APLWTLGPFC ACTSANNNTY WCLRTINETH NFLFCEFATG
FLEYFDLNTD PYQLINAVNT LDRDVLNQLH VQLMELRSCK GYKQCNPRTR NMDLGLKDGS
YEQYRQFQRR KWPDVKRPSS AKSLGQLWEG WEG
//
