ID   A0A093F0Q3_TYTAL        Unreviewed;       681 AA.
AC   A0A093F0Q3;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Nucleolar GTP-binding protein 2 {ECO:0000256|RuleBase:RU364023};
DE   Flags: Fragment;
GN   ORFNames=N341_10430 {ECO:0000313|EMBL:KFV50060.1};
OS   Tyto alba (Barn owl).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX   NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV50060.1, ECO:0000313|Proteomes:UP000054190};
RN   [1] {ECO:0000313|EMBL:KFV50060.1, ECO:0000313|Proteomes:UP000054190}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV50060.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: GTPase that associates with pre-60S ribosomal subunits in the
CC       nucleolus and is required for their nuclear export and maturation.
CC       {ECO:0000256|RuleBase:RU364023}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU364023}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2
CC       subfamily. {ECO:0000256|RuleBase:RU364023}.
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DR   EMBL; KK384106; KFV50060.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093F0Q3; -.
DR   Proteomes; UP000054190; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   CDD; cd01858; NGP_1; 1.
DR   Gene3D; 1.10.1580.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030378; G_CP_dom.
DR   InterPro; IPR024929; GNL2_CP_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR   InterPro; IPR012971; NOG2_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11089; GTP-BINDING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR11089:SF9; NUCLEOLAR GTP-BINDING PROTEIN 2; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   Pfam; PF08153; NGP1NT; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51721; G_CP; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU364023};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU364023};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364023};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054190}.
FT   DOMAIN          167..328
FT                   /note="CP-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51721"
FT   REGION          439..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          490..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          579..681
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..521
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..636
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        642..666
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        667..681
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV50060.1"
FT   NON_TER         681
FT                   /evidence="ECO:0000313|EMBL:KFV50060.1"
SQ   SEQUENCE   681 AA;  77942 MW;  6652C0B51C063CC3 CRC64;
     IHMFSHFSLR NKYGKVIKPL QYQSTVAPGT VARVEPNIKW FGNTRVIKQS SLQKFQEEME
     TVMKDPYRVV MKQRKLPMSL FYDRIKPHNS RVHILDTETF ETTFGPKSQR KRPNLSASDV
     QSLVENAEAS SVSYDQGKDR DLVTEDTGVR DEAQEEIYKK GQSRRIWGEL YKVIDSSDVV
     VQVLDARDPM GTRSPHVESY LKKEKHWKHL IFVLNKCDLV PTWATKRWVA VLSQEYPTLA
     FHASLTNPFG KGAFIQLLRQ FGKLHSDKKQ ISVGFIGYPN VGKSSVINTL RSKKVCNVAP
     IAGETKVWQY ITLMRRIFLI DCPGVVYPSG DTETDIVLKG VVQVEKIKSP EDHISAVLQR
     AKPEYIRKTY KIDSWKDAEE FLEKLAARTG KLLKGGEPDM QTVSKMVLND WQRGRIPFFV
     KPPNAETGPQ PPALEVAVTS GQDNKEEKMS EPVTSTVEPA EEKSNTDTEI KQLMSHVRQN
     FGRINVAPQF SEEDLIPVDV PGFDDTDSDS SGEEEQEEEK EENEQHQNSV EEESQLTVPS
     AKESSKAVLK ALDEKIAKYK KFLDKAKAKR FSAIRIPKEL SEKVFAKSMQ KSEEPKETEG
     RGSTENKRKR KAEEDDDDHL GEQPCKKLTS KERRRAERQQ RSKKVGVRYY ETHNVKNKNK
     NKKKTGLEGQ RSKHKKHKHK Q
//