ID A0A093F1A3_GAVST Unreviewed; 708 AA.
AC A0A093F1A3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Transmembrane protease serine 7 {ECO:0000313|EMBL:KFV47929.1};
DE Flags: Fragment;
GN ORFNames=N328_06531 {ECO:0000313|EMBL:KFV47929.1};
OS Gavia stellata (Red-throated diver) (Colymbus stellatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gaviiformes; Gaviidae; Gavia.
OX NCBI_TaxID=37040 {ECO:0000313|EMBL:KFV47929.1, ECO:0000313|Proteomes:UP000054313};
RN [1] {ECO:0000313|EMBL:KFV47929.1, ECO:0000313|Proteomes:UP000054313}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N328 {ECO:0000313|EMBL:KFV47929.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; KK614610; KFV47929.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093F1A3; -.
DR Proteomes; UP000054313; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 2.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 2.
DR Gene3D; 3.30.70.960; SEA domain; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR24252:SF8; ACROSIN; 1.
DR PANTHER; PTHR24252; ACROSIN-RELATED; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF00057; Ldl_recept_a; 2.
DR Pfam; PF01390; SEA; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00192; LDLa; 3.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 2.
DR SUPFAM; SSF82671; SEA domain; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS50068; LDLRA_2; 2.
DR PROSITE; PS50024; SEA; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Hydrolase {ECO:0000313|EMBL:KFV47929.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:KFV47929.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054313};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:KFV47929.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 72..200
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 209..326
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 331..444
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 574..708
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT DISULFID 450..462
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 457..475
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 469..484
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 525..537
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 545..560
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV47929.1"
FT NON_TER 708
FT /evidence="ECO:0000313|EMBL:KFV47929.1"
SQ SEQUENCE 708 AA; 79645 MW; 46A14BC8B9BF00FA CRC64;
ANISVQTVAA EDKLAKRILA RKKHGKLKLK KKDKLLWNLQ NKIILFTLIL FILGVVTWTL
LWLFIVQAEN KDALYFVGLF RVANIEFLPE YRQKESKEFL SVAQNVQHVM NLVYTTSSFS
KFYKQSTVSE VSNNNNGGLL IHFWIVFVVP QAKGQVLCED CVAAILKDSI QTSIINRTSV
GSLQGLAVDM DSIVLSAGLR SDYWSTTGTG TNCMYDLYAD RLHEHFPLDI HAATEGAICY
FKLIASVGHL IRLSIVSLQI EADNCITDSL TIYDSLMPIK HKILYRACEP ADSLVSLVST
NNLMLVMFKA AQIKEQREFH GYFEVITQER CGKAIVTKEK TGYEGRITSP YYPSYYPPKC
LCAWNFQTPQ KSLGVALKFH NYTISEKNIK GCERGWWKIN EQMYCGYYVD HQTIFHIASS
AVNIELQCSS EVSEKPLLVE YGSYNISQPC PPGHFKCSTG LCIQQVQRCD GINNCFDESD
ELFCVVPERN CNSSFTTQDN PLACNGVSDC ENGEDEQNCT HSIPCTSHTF KCRNNICIRK
QNAKCDGTVD CIDGSDESSC SCGSSRSSNP ISRIVGGMNT EEGEWPWQVS LHFVGAAYCG
ASVIAKEWLV SAAHCFQGSK LADPRAWRAH LGMQTQGRAK FVSAVRRIIV HEYYNSRNYD
YDIALLQLSK PWPDTMSQVI QPICVPPFSH KVRSGDKCWI TGWGQKQE
//
