ID A0A093FA56_TYTAL Unreviewed; 671 AA.
AC A0A093FA56;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|EMBL:KFV54572.1};
DE Flags: Fragment;
GN ORFNames=N341_00748 {ECO:0000313|EMBL:KFV54572.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV54572.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV54572.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV54572.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK390756; KFV54572.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093FA56; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd01260; PH_CNK_mammalian-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010599; CNK2/3_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR PANTHER; PTHR12844:SF21; CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2; 1.
DR Pfam; PF06663; CNK2_3_dom; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KFV54572.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Transferase {ECO:0000313|EMBL:KFV54572.1}.
FT DOMAIN 28..110
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 383..482
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 137..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 575..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..525
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..671
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV54572.1"
FT NON_TER 671
FT /evidence="ECO:0000313|EMBL:KFV54572.1"
SQ SEQUENCE 671 AA; 76200 MW; 25320C75BAF9D0BF CRC64;
CKTLSGVCDH IISLSSDPLV SQSAHLEVIQ LTNIKPSEGL GMYIKSTYDG LHVITGTTEN
SPADRCKKIH AGDEVIQVNH QTVVGWQLKN LVNALREDPS GVILTLKKRP QSMLTSAPAL
LKNMRWKPLA LQPLIPRSPT SSVATPSSTI STPTKRDSSA LQDLYIPPPP TEPYVPRDEK
GNLPCDDVGR HIVGKPVHTG SESPNSFLDQ EYRKRFNVVE EDAVLYCYEY EKGRTSGPGR
RESTPTYGKL RPISMPVEYN WVGDYEDPNK IKRDSRRENS LLRYMSNEKI GQEDYMFQRN
SKKDTGKKSK KKGDKSGSPS HYSLLPSLQM DSLRQEVMGT PGPETALYHT FQQSSLQQKS
KKKNKAPIPG KSKRRISCKD LGRGDCEGWL WKKKDAKSYF SQKWKKYWFV LKDTSLYWYI
NEEDEKAEGF ISLPEFKIDR ASECRKKYAF KACHPKIKSF YFAAEHLDDM NRWLNRINML
AAGYAERERI KQEQDYWSES DKEEADTPST PKQDSPPPPY DTYPRPPSMS CASPYVEPKH
SRLSSTETSQ SQSSHEEFRP EVPLPLEDSV FSEAAVVSPE HRRQSTLPTQ KCHLQDHYGP
FPLVEGERMQ VLNGNGGKPR SFTLPRDSGF NHCCQSLSVG ATDHHEEAQQ KDVEEEEEEE
GKAAEENQED K
//
