ID A0A093FDS4_TYTAL Unreviewed; 1169 AA.
AC A0A093FDS4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=ATP-binding cassette sub-family C member 8 {ECO:0000313|EMBL:KFV55847.1};
DE Flags: Fragment;
GN ORFNames=N341_02083 {ECO:0000313|EMBL:KFV55847.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV55847.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV55847.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV55847.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts with KCNJ11. {ECO:0000256|ARBA:ARBA00011132}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KK393310; KFV55847.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093FDS4; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008281; F:sulfonylurea receptor activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR CDD; cd18591; ABC_6TM_SUR1_D1_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR000844; ABCC8.
DR InterPro; IPR000388; ABCC8/9.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF187; ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 1.
DR PRINTS; PR01093; SULFNYLUR1.
DR PRINTS; PR01092; SULFNYLUREAR.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:KFV55847.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..559
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 956..974
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1019..1038
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1105..1131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 266..568
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 643..882
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 967..1169
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV55847.1"
FT NON_TER 1169
FT /evidence="ECO:0000313|EMBL:KFV55847.1"
SQ SEQUENCE 1169 AA; 132260 MW; F14BC5B01D4439D4 CRC64;
LLLLRKLFKI FFSCLGWGSQ SSKVHIHHST WLHFPGHNLR WILTFILLFV LVCEIAEGIV
SDGVSESRHL HLYMPAGMAF LAAITSVVYY HNIETSNFPK LLIALLFYWT LAFITKTIKF
VKFCDNGVGF SQLRFCLTGL LVVLYGMLLA VEINVIRVRR YVFFKTPKEV KPPEDLQDLG
VRFLQPFVNL LSKGTYWWMN TFIKTAHKKP IDLKTIGKLP IAMRALTNYI RLNEAFEAQK
NKRSSSPQGS RSIWRALCCA FGRPLLLSST FRILADLLGF TGPLCISGIV HNVGKGNNTI
RPQTKILGVF FISSQEFLSN AYVLAVLLFF ALLLQRTFLQ ASYYVAIETG INLRGAIQTK
IYNKIMQLST SNMSMGEMTA GQICNLVAID TNQLMWFFFL CPNLWAMPVQ IIVGVLLLYY
LLGISALIGA AVIIVLAPVQ YFVATKLSQA QRSTLEYSNE RLKKTNEMLR GIKLLKLYAW
EHIFHSSVEE TRQKEMTSLK SFALYTSISI FMNAAIPIAA VLITFVVHAH LTTKADFSPS
VAFASISLFH ILVSPLFLLS SVVRSTVKAL VSVQKLSEFL SSEEIGEEHD KSSELRRADN
HSKYQAVPLK VVNRKRPARE DWNNYSSHMR RPINITEADD FCVKITNGFF TWTPEGPPAL
SNIDIRIPQG QLTMIVGQVG CGKSSLLLAI LGEMQKISGN IFWSRVKQAI YSIKRNRKRG
SVAYASQKPW LLNATVEENI TFESPFNKQR YKAVIDACSL QPDIDILPHG DQTQIGERGI
NLSGGQRQRI SVARALYQQT NVVFLDDPFS ALDIHLSDHL MQEGILKMLR EDKRTIVLVT
HKLQYLPHAD WIIAMKDGNI QREGTLKDIQ KSESELFEHW KTLMNRQDQE LEKETIIERK
TVLERTNLRR TMYSREALLK DDEEDEEEVT ESDDEDNLSS VLHQRAKMPW RACGKYLSAA
GILLLPLLVL SQLLKHTVMV AIDYCLACWT SAAISEKTEP GLKNCSHCED FNHSPYSKVF
SILCCLGIVL CLVTSIAVEW TGLKVTKKLH SSLLNKIILA PMRFFETTPL GSILNRFSAD
CNTIDQHIPA TLECLSRSTL LCVSALAVIS YVTPMFLIAL VPLAIMCYFI QKYFRVASRD
LQQLDDSTQL PLLSHFSETV EGLTTIRAF
//
