ID   A0A093FJP2_TYTAL        Unreviewed;       612 AA.
AC   A0A093FJP2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
DE   Flags: Fragment;
GN   ORFNames=N341_06129 {ECO:0000313|EMBL:KFV56840.1};
OS   Tyto alba (Barn owl).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX   NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV56840.1, ECO:0000313|Proteomes:UP000054190};
RN   [1] {ECO:0000313|EMBL:KFV56840.1, ECO:0000313|Proteomes:UP000054190}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV56840.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR   EMBL; KK395140; KFV56840.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093FJP2; -.
DR   Proteomes; UP000054190; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   CDD; cd17978; DEXHc_DHX33; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFV56840.1};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFV56840.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806,
KW   ECO:0000313|EMBL:KFV56840.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054190}.
FT   DOMAIN          1..157
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          175..355
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV56840.1"
FT   NON_TER         612
FT                   /evidence="ECO:0000313|EMBL:KFV56840.1"
SQ   SEQUENCE   612 AA;  68790 MW;  4ACA96D0FE5A8542 CRC64;
     LGETGSGKTT QVPQYLYEAG IGRQGIIAVT QPRRVAAIAL ATRVSDEKKT ELGKLVGYTV
     RFDDLTSDET RIKFLTDGML LREAIGDPML RKYSIVILDE AHERTIHTDV LFGVVKAAQK
     KRKELGKLPL KVIIMSATMD VDQFSQYFNG APVLYLEGRQ HPIQIFYTKQ PQSDYLQAAL
     VSVFQIHQEA PPSQDILVFL TGQEEIEAMT KTCRDIAKHL PDGCPQMMVM PLYASLPYSQ
     QLRVFQAAPK GCRKVILSTN IAETSITIAG IKYVVDTGMV KAKKYSPETG LEVLAVQRVS
     KAQAWQRTGR AGREDSGICY RLYTEDEFEK FDKMTIPEIQ RCNLASVVLQ LLAMRIPNVL
     TFDFMSKPSP DAIQAAIEQL DLLGAVERKE DQLVLTPLGR KMAAFPLEPK FSKTILLSPK
     FHCTEEILTI VSLLSVDSVL YNPPAQRDEV QSVRKKFISN EGDHLTLLSM YRAFKNVSGN
     KEWCKENFVN SRNMMLVSDV RAQLRDICVK LSMPIESSRS DTGNIRRCLA HSLFMNAAEL
     QPDGTYSTVD SHQLVAIHPS SVLFHCKPAC VVYNGLLHTN KCYMRDLCVV DADWLFDAAP
     DYFRRKLRTA KN
//