ID A0A093FK70_TYTAL Unreviewed; 598 AA.
AC A0A093FK70;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
GN ORFNames=N341_08817 {ECO:0000313|EMBL:KFV58132.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV58132.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV58132.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV58132.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC 2.A.22) family. {ECO:0000256|RuleBase:RU003732}.
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DR EMBL; KK397693; KFV58132.1; -; Genomic_DNA.
DR RefSeq; XP_009970750.1; XM_009972448.1.
DR AlphaFoldDB; A0A093FK70; -.
DR OMA; TIWFVSR; -.
DR OrthoDB; 3084493at2759; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005332; F:gamma-aminobutyric acid:sodium:chloride symporter activity; IEA:InterPro.
DR GO; GO:0006836; P:neurotransmitter transport; IEA:InterPro.
DR CDD; cd11506; SLC6sbd_GAT1; 1.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR002980; Na/ntran_symport_GABA_GAT1.
DR InterPro; IPR037272; SNS_sf.
DR NCBIfam; NF037979; Na_transp; 1.
DR PANTHER; PTHR11616:SF138; SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 1; 1.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 1.
DR PRINTS; PR01195; GAT1TRNSPORT.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR PROSITE; PS00754; NA_NEUROTRAN_SYMP_2; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Symport {ECO:0000256|RuleBase:RU003732};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003732};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT TRANSMEM 52..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 575..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..598
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 67090 MW; CC38F9085A6BA657 CRC64;
MATNGTKVAD GQISTEVDAS ITNDKPKTLV VKVQKKKTDL PDRDTWKGKF DFLMSCVGYA
IGLGNVWRFP YLCGKNGGGA FLIPYFLTLI FAGVPLFLLE CSLGQYTSIG GLGVWKLAPM
FKGVGLAAAV LSFWLNIYYI VIISWAIYYL YNSFTTTLPW KHCENPWNTD RCFSNYTLAN
TTNMTSAVVE FWERNMHQMT DGLEKPGQIR WPLAITLAIA WILVYFCIWK GVGWTGKVVY
FSATYPYVML LILFFRGVTL PGAKEGILFY ITPNFSKLSD SEVWLDAATQ IFFSYGLGLG
SLIALGSYNP FHNNVYRDSI IVCCINSCTS MFAGFVIFSI VGFMANVTKR PIADVAASGP
GLAFLAYPEA VTQLPISPLW AILFFSMLLM LGIDSQFCTV EGFITALVDE FPKLLRNRRE
IFIAVVCIVS YLIGLSNITQ GGIYVFKLFD YYSASGMSLL FLVFFECISI SWCYGVNRFY
DNIQEMVGYR PCIWWKLCWS FFTPIIVAGV FIFSAVQMTP LTMGSYVFPK WGQGVGWFMA
LSSMVLIPGY MAYMFLTLKG SLKQRIQVMI QPSEDITHPE NGPDQAQQSN SANKEAYI
//
