ID A0A093FNV0_TYTAL Unreviewed; 422 AA.
AC A0A093FNV0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=protein disulfide-isomerase {ECO:0000256|ARBA:ARBA00012723};
DE EC=5.3.4.1 {ECO:0000256|ARBA:ARBA00012723};
DE Flags: Fragment;
GN ORFNames=N341_02489 {ECO:0000313|EMBL:KFV59417.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV59417.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV59417.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV59417.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; KK400004; KFV59417.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093FNV0; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd03000; PDI_a_TMX3; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46426; PROTEIN DISULFIDE-ISOMERASE TMX3; 1.
DR PANTHER; PTHR46426:SF1; PROTEIN DISULFIDE-ISOMERASE TMX3; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR PRINTS; PR00421; THIOREDOXIN.
DR SUPFAM; SSF52833; Thioredoxin-like; 2.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:KFV59417.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 1..97
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 374..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..422
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV59417.1"
FT NON_TER 422
FT /evidence="ECO:0000313|EMBL:KFV59417.1"
SQ SEQUENCE 422 AA; 47951 MW; EB658744609A10D4 CRC64;
FKENRKDDIW LVDFYAPWCG HCKKLEPVWN EVGIEMKSMG SPVKVGKMDA TSFSSIASEF
GVRGYPTIKL LKGDLAYNYR GPRTKDDIIE FANRVAGPLI RPLPSQHMFE HVQKRHRVLF
VYVGGESPLK EKYIEVASEL IVYTYFFSAS EDVLPEYVTL PELPAVVVFK DGTYFVYDEY
EDGDLSSWIN RERFQGYLNV DGFTLYELGD TGKLVAIAVI DDKNSSVEHT RLKSIIQEVA
RDYRDHFHRD FQFGHMDGND YINSLLMDDL TIPTIVVLNT SNQQYFLPDR HIENTEDMVQ
FINNILDGTA EAQGGDGLLQ RIKRIIYDAK STVVSVFKSS PLLGCFLFGL PLGVISIMCY
GICTADTDGG VDEHEAAKKE NGDRELTDEG SEEEQEEEKN GKYAELSDGE LKQKDIIEKK
KD
//
